2008 Fibroblast Growth Factors in Development & Disease Gordon Research Conferenc

描述（由申请人提供）：本申请要求部分资助将于2008年3月2日至7日在意大利巴尔加的Il Ciocco酒店和度假村举行的2008年戈登成纤维细胞生长因子发育和疾病研究会议。这次会议的广泛和长期目标是增加我们对1. FGF及其受体调节各种器官发育的机制; 2. FGF在骨骼生物学和高级脑功能中功能的分子基础; 3. FGF信号传导促进多种病理学的方式;和4. FGF信号在组织稳态、修复和再生中的作用。通常情况下，研究这些问题的大多数科学家不参加共同会议。因此，这次多学科会议的具体目的是提供一种机制，在一个单一的论坛上，汇集了在FGF和FGF受体结构-功能分析，信号传导领域工作的不同研究人员，以及FGF信号传导途径在发育，器官功能，发病机制以及细胞和组织生物学中的作用。 为期五天的会议将在一个相对孤立的环境中召开，约有45名发言者代表FGF研究的关键领域，共有约135名与会者。该计划将开始两个主题演讲，一个是FGF受体的结构和功能，另一个是FGF信号在发育和疾病中的功能。随后将举行八次会议，广泛讨论FGF在器官发生、神经系统发育、骨骼生物学、神经系统功能和修复、肿瘤发生、组织稳态、组织修复以及干细胞和再生中的功能。这一应用的意义在于，关于FGFs在发展和疾病中的戈登研究会议将提供一个独特而及时的论坛。其多样和令人振奋的气氛预计将通过促进与会者之间讨论和传播新的想法和协作，为取得进展开辟道路。

DESCRIPTION (provided by applicant): This application requests funding to partially support the 2008 Gordon Research Conference on Fibroblast Growth Factors in Development and Disease, to be held on March 2-7, 2008 at Il Ciocco Hotel and Resort, Barga, Italy. The broad and long term goal of this conference is to increase our understanding of 1. the mechanisms by which FGFs and their receptors regulate the development of various organs; 2. the molecular basis for FGF function in skeletal biology and higher brain function; 3. the ways in which FGF signaling contributes to diverse pathologies; and 4. the role of FGF signaling in tissue homeostasis, repair, and regeneration. Typically, the majority of scientists working on these problems do not attend common meetings. The specific aim of this multidisciplinary conference is therefore to provide a mechanism for bringing together, in a single forum, a diverse group of researchers working in areas of FGF and FGF receptor structure-function analysis, signaling, and the roles of FGF signaling pathways in development, organ function, pathogenesis, as well as cell and tissue biology. The five-day conference will be convened in a relatively isolated setting, with approximately 45 speakers that represent critical areas of FGF research and a total of approximately 135 participants. The program will begin with two keynote addresses, one on FGF receptor structure and function, and the other on the function of FGF signaling in development and disease. Eight sessions will follow that broadly address FGF function in organogenesis, development of the nervous system, skeletal biology, nervous system function and repair, tumorigenesis, tissue homeostasis, tissue repair, as well as stem cells and regeneration. The significance of this application is that the Gordon Research Conference on FGFs in Development and Disease will provide a unique and timely forum. Its diverse and stimulating atmosphere is expected to open avenues for progress by promoting the discussion and dissemination of new ideas and collaborations among the participants.