SPATIAL AND TEMPORAL PATTERNS OF FUNCTIONAL ACTIVATION

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 该项目的主要目标是（i）对从[15 O]水PET和1.5T和4 T fMRI神经认知研究中获得的功能激活的空间和时间模式进行建模和可视化，（ii）系统地评估受试者间脑图像配准的自动算法的准确性，以及（iii）为了量化配准算法的性能如何作为用于驱动配准的特征的层次结构和用于计算配准的优度的特征的函数而变化，登记

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The major goals of this project are (i) to model and visualize spatial and temporal patterns of functional activation obtained from [15O]water PET and 1.5T and 4T fMRI neurocognitive studies, (ii) to systematically evaluate the accuracy of automated algorithms for intersubject brain image registration, and (iii) to quantify how the performance of registration algorithms varies as a function of the hierarchy of features used to drive the registration and the features used to compute goodness of registration.