RODENT IMAGING AND SPECTROSCOPY FACILITY
RODENT IMAGING AND SPECTROSCOPY FACILITY
批准号:
7724109
负责人:
Craig R Malloy
金额:
$1.05万
依托单位国家:
美国
项目类别:
财政年份:
2008
资助国家:
美国
项目状态:
已结题
起止时间:
2008-09-01 至 2009-08-31
关键词:
ArtsCell NucleusChemicalsComputer Retrieval of Information on Scientific Projects DatabaseCouplingFatty acid glycerol estersFundingGlycogenGrantImageInstitutionMeasurementPatternPredispositionRangeResearchResearch PersonnelResolutionResourcesRodentSourceSpectrum AnalysisUnited States National Institutes of Healthimprovedinstrument
中文摘要
这个子项目是许多研究子项目中的一个
由NIH/NCRR资助的中心赠款提供的资源。子项目和
研究者(PI)可能从另一个NIH来源获得了主要资金,
因此可以在其他CRISP条目中表示。所列机构为
研究中心,而研究中心不一定是研究者所在的机构。
2007年将安装两台新的最先进的磁共振仪器。 目标是为广泛的用户提供7 T和9.4T的成像和光谱。 啮齿动物研究的高场具有多种优势,包括提高的灵敏度、提高的易感性依赖性测量(例如肌细胞内脂肪与肌细胞外脂肪的分辨率)、更宽的化学位移分散、更简单的J耦合模式和更长的T1,这将有利于化学交换依赖性现象。7 T将是专用于1H成像的16 cm RT孔径仪器; X射线细胞核不可用。 9.4T将是一个21 cm RT口径的仪器,致力于超高场成像和光谱学研究,包括13 C,31 P,23 Na等,以及最佳的糖原成像。
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
Two new state-of-the-art MR instruments will be installed in 2007. The objective is to provide imaging and spectroscopy at 7T and 9.4T for a wide range of users. The high fields for rodent studies have multiple advantages, including improved sensitivity, improved susceptibility - dependent measurements such as resolution of intra- from extra-myocellular fat, wider chemical shift dispersion, simpler J coupling patterns, and longer T1s that will benefit chemical exchange-dependent phenomena. The 7T will be a 16 cm RT bore instrument dedicated exclusively to 1H imaging; x nucleus will not be available. The 9.4T will be a 21 cm RT bore instrument devoted to research in ultra-high field imaging and spectroscopy including 13C, 31P, 23Na, etc., as well as optimal glycogen imaging.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
A Clinical MR Scanner for Imaging Hyperpolarized Carbon-13
-
批准号:7842399
-
项目类别:
-
资助金额:$223.73万
-
财政年份:2011
-
负责人:Craig R Malloy
-
依托单位:
IN VIVO 13C NMR SPECTROSCOPY
-
批准号:8363886
-
项目类别:
-
资助金额:$25.73万
-
财政年份:2011
-
负责人:Craig R Malloy
-
依托单位:
ANNUAL SYMPOSIUM
-
批准号:8363900
-
项目类别:
-
资助金额:$4.82万
-
财政年份:2011
-
负责人:Craig R Malloy
-
依托单位:
FAT AND CARBOHYDRATE METABOLISM IN SKELETAL MUSCLE
-
批准号:8171635
-
项目类别:
-
资助金额:$10.46万
-
财政年份:2010
-
负责人:Craig R Malloy
-
依托单位:
ANNUAL SYMPOSIUM
-
批准号:8171649
-
项目类别:
-
资助金额:$3.14万
-
财政年份:2010
-
负责人:Craig R Malloy
-
依托单位:
FAT AND CARBOHYDRATE METABOLISM IN SKELETAL MUSCLE
-
批准号:7956948
-
项目类别:
-
资助金额:$17.84万
-
财政年份:2009
-
负责人:Craig R Malloy
-
依托单位:
MOUSE METABOLIC PHENOTYPING CENTER
-
批准号:7956958
-
项目类别:
-
资助金额:$8.92万
-
财政年份:2009
-
负责人:Craig R Malloy
-
依托单位:
ANNUAL SYMPOSIUM
-
批准号:7956968
-
项目类别:
-
资助金额:$5.35万
-
财政年份:2009
-
负责人:Craig R Malloy
-
依托单位:
MOUSE METABOLIC PHENOTYPING CENTER
-
批准号:7724108
-
项目类别:
-
资助金额:$5.23万
-
财政年份:2008
-
负责人:Craig R Malloy
-
依托单位:
FAT AND CARBOHYDRATE METABOLISM IN THE LIVER AND SKELETAL MUSCLE
-
批准号:7724099
-
项目类别:
-
资助金额:$10.46万
-
财政年份:2008
-
负责人:Craig R Malloy
-
依托单位:
ANNUAL SYMPOSIUM
-
批准号:7724118
-
项目类别:
-
资助金额:$3.14万
-
财政年份:2008
-
负责人:Craig R Malloy
-
依托单位:
ULTRA-HIGH FIELD IMAGING AND SPECTROSCOPY OF HUMAN SUBJECTS
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批准号:7724100
-
项目类别:
-
资助金额:$3.14万
-
财政年份:2008
-
负责人:Craig R Malloy
-
依托单位:
Skeletal Mitochondrial Function, Body Weight, and Diabetes, Project 5 of 10
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批准号:7653675
-
项目类别:
-
资助金额:$38.5万
-
财政年份:2007
-
负责人:Craig R Malloy
-
依托单位:
MOUSE METABOLIC PHENOTYPING CENTER
-
批准号:7600842
-
项目类别:
-
资助金额:$6.05万
-
财政年份:2007
-
负责人:Craig R Malloy
-
依托单位:
Skeletal Mitochondrial Function, Body Weight, and Diabetes, Project 5 of 10
-
批准号:7883234
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项目类别:
-
资助金额:$38.12万
-
财政年份:2007
-
负责人:Craig R Malloy
-
依托单位:
RODENT IMAGING AND SPECTROSCOPY FACILITY
-
批准号:7600843
-
项目类别:
-
资助金额:$1.51万
-
财政年份:2007
-
负责人:Craig R Malloy
-
依托单位:
FAT AND CARBOHYDRATE METABOLISM IN THE LIVER AND SKELETAL MUSCLE
-
批准号:7600833
-
项目类别:
-
资助金额:$15.12万
-
财政年份:2007
-
负责人:Craig R Malloy
-
依托单位:
Skeletal Mitochondrial Function, Body Weight, and Diabetes, Project 5 of 10
-
批准号:8106278
-
项目类别:
-
资助金额:$37.74万
-
财政年份:2007
-
负责人:Craig R Malloy
-
依托单位:
ANNUAL SYMPOSIUM
-
批准号:7600852
-
项目类别:
-
资助金额:$4.54万
-
财政年份:2007
-
负责人:Craig R Malloy
-
依托单位:
Skeletal Mitochondrial Function, Body Weight, and Diabetes, Project 5 of 10
-
批准号:7501335
-
项目类别:
-
资助金额:$38.5万
-
财政年份:2007
-
负责人:Craig R Malloy
-
依托单位:
海外基金