Home Ambulatory EEG with Video Monitoring

描述（由申请人提供）：本项目将开发一种先进的无线家庭视频脑电图（EEG）系统，该系统基于超小型动态EEG记录仪，结合新的同步无线高质量视频记录技术。癫痫的初步诊断通常基于癫痫发作的描述，神经系统检查和常规EEG研究。然而，癫痫发作的原因可能仍然不清楚，可以使用长期EEG监测来确认儿童和成人的诊断。在这些长期研究中经常使用动态EEG记录器，允许患者带着记录器回家并持续监测癫痫发作活动。对于当前可用的动态EEG记录器，记录器的尺寸和不存在或有限的视频记录能力减少了动态EEG的益处。视频监测可以在癫痫的诊断中发挥不可或缺的作用。来自大脑的记录沿着视频记录使医生能够记录和分析患者的癫痫发作。视频头皮脑电图（v-EEG）是一种基础技术，用于评估出现与神经症状相关的短暂性、阵发性临床事件的患者。动态脑电图记录器已经存在多年，在过去的十年中，它们的尺寸已经减小，并且包括有限的视频记录。然而，即使是最先进的产品的尺寸仍然是一个障碍，特别是对于小孩子来说，这使得家庭监控变得困难。移动视频监控仅限于一台有线摄像机（如果可用）。最近几种使能技术的广泛商业化使得有可能创建具有同步视频的微型动态EEG记录器，其大小约为当前可用系统的十分之一。拟定的高级动态v-EEG将在马约诊所根据金标准临床v-EEG系统进行开发和评价。 公共卫生相关性：最常见的神经系统疾病之一是癫痫。癫痫是指有无缘无故的癫痫发作的倾向，并包括许多不同的综合征。它的患病率为0.5%到1%。这相当于美国约200万人。通常规定用于诊断视频头皮脑电图（v-EEG）监测的昂贵的长期住院。如果能够解决尺寸、易用性和足够的视频问题，则在患者家中进行的动态v-EEG可以节省大量成本并使患者受益。

DESCRIPTION (provided by applicant): This project will develop an advanced wireless home video electroencephalograph (EEG) system based on an ultra-miniature ambulatory EEG recorder combined with new synchronized wireless high-quality video recording technology. An initial diagnosis of epilepsy is often based on the description of a seizure, a neurological examination, and routine EEG studies. However, the cause of a seizure may still be unclear and longer term EEG monitoring can be used to confirm the diagnosis in both children and adults. Ambulatory EEG recorders are often used in these long term studies allowing a patient to go home with the recorder attached and continuously monitoring seizure activity. With currently available ambulatory EEG recorders, the size of the recorder and non-existent or limited video recording capability diminishes the benefits of ambulatory EEG. Video monitoring can play an integral role in the diagnosis of epilepsy. Recordings from the brain along with video recordings allow physicians to document and analyze patients' seizures. Video scalp electroencephalography (v-EEG) is a cornerstone technology for the evaluation of patients presenting with transient, paroxysmal clinical events associated with neurological symptoms. Ambulatory EEG recorders have existed for years and in the past decade they have been reduced in size and included limited video recording. However, the size of even the most advanced products remains an obstacle, particularly for small children, making home monitoring difficult. Ambulatory video monitoring is limited to a single tethered camera, if available. The recent widespread commercialization of several enabling technologies makes possible the creation of a miniature ambulatory EEG recorder with synchronized video approximately one-tenth the size of currently available systems. The proposed advanced ambulatory v-EEG will be developed and evaluated against a gold-standard clinical v-EEG system at the Mayo clinic. PUBLIC HEALTH RELEVANCE: One of the most common neurological diseases is epilepsy. Epilepsy refers to the tendency to have unprovoked seizures, and encompasses a number of different syndromes. It has a prevalence of 0.5 to one percent. This translates to approximately two million persons in the United States. Expensive long term hospital stays for diagnostic video scalp electroencephalography (v-EEG) monitoring are typically prescribed. Ambulatory v-EEG carried out in the patient home can provide a large cost savings and patient benefit if size, ease of use, and adequate video issues can be resolved.