Exposure Core

暴露评估核心将负责收集数据，以便能够估计以下方面的暴露 这三项健康研究。这将包括：1)收集和质量检查常规空气监测数据 空气资源委员会；2)建立多环芳烃(PAHs)采样和 在贝克尔斯菲尔德的一个中心地点发现内毒素，并在那里收集和分析样本一年，以确定 多环芳烃和内毒素的时间变异性；3)采集多环芳烃和内毒素的同期样本 多个地点的内毒素持续1-2个月；4)探索常规空气的变化空间格局 污染物、多环芳烃和内毒素。需要了解常规收集的污染物的数据 社区的当前暴露梯度，这将因空气污染物而异，并有助于健康 项目3的影响分析。PM2.5的化学成分将包括元素碳、有机 碳、硝酸盐、硫酸盐和微量金属。此外，还将在另外两个空气监测站收集PAH数据 在2010/201秋/冬季为期两个月的空间站，将在5个其他空气中收集陆地内毒素样本 2010年夏季为期1个月的监测站。我们正在收集这些信息，以改善 了解这些污染物在大贝克斯菲尔德地区的空间变异性对 中心的设计。此区域当前不存在此类型的空间数据。这些暴露数据将是 被健康研究用作他们为预科中心计划的工作的一部分，但也将指导我们规划 当中心是一个完整的中心时，它将需要收集的数据。

The Exposure Assessment Core will be responsible for collecting data to enable estimates of exposures for the three health studies. This will include: 1) collecting and quality checking routine air monitoring data from the Air Resources Board; 2) establishing sampling for polycyclic aromatic hydrocarbons (PAHs) and endotoxin at a central site in Bakersfield and collecting and analyzing samples there for one year to establish the temporal variability for PAHs and endotoxin; 3) collecting contemporaneous samples for PAHs and endotoxin at multiple locations for 1-2 months; 4) exploring the varying spatial pattems for routine air pollutants, PAHs and endotoxin. The data for routinely collected pollutants are needed to understand current exposure gradients in the communities, which will differ by air contaminant, and to facilitate health effects analyses for Project 3. The PM2.5 chemical constituents will include elemental carbon, organic carbon, nitrate, sulfate, and trace metals. In addition, PAH data will be collected at two other air monitoring stations for a 2 month period in fall/winter 2010/201 land endotoxin samples will be collected at 5 other air monitoring stations for a 1 month period in summer 2010. These are being collected to improve the understanding of spatial variability ofthese pollutants in the greater Bakersfield area which is critical to the design of the center. No spatial data of this type currently exist for this area. These exposure data will be used by the health studies as part of their planned work for the pre-center, but will also guide us in planning the data the center will need t o collect when it is a full center.