CTSA INFRASTRUCTURE FOR AIDS RESEARCH

该子项目是对CTSA供资的百分比的估计， 用于广泛的研究领域（艾滋病研究，儿科研究，或 临床试验）。 列出的总成本仅为CTSA金额的估算 基础设施走向这一领域的研究，而不是直接提供资金， 向子项目或子项目工作人员提供NCRR补助金。 俄勒冈州的生物医学研究机构是杰出的，并准备在临床/转化研究的重大扩张。我们建议成立俄勒冈州临床和转化科学研究所（OCTSI）。OCTSI将从根本上改变生物医学研究，为人类创造一个充满活力的学术家园。 临床/翻译研究。它将利用现有的优势，消除研究速度和增长的障碍。在OCTSI的核心是俄勒冈州健康与科学大学（OHSU）和凯撒永久的健康研究中心（KPCHR）之间的强大合作伙伴关系，汇集了一个 强大的生物医学研究大学和创新的实践为基础的研究中心与大量的患者群体。该合作为人类研究领域的扩展提供了独特的机会，并为人类健康的重大进步奠定了基础。 俄勒冈州的临床和translatlonal研究的转型得到了以下方面的加强：+对OCTSI的强大机构支持，表现为重大的行政变革以及大量财政和空间资源的承诺+OHSU和KPCHR的学术学院充分支持OCTSI倡议和开发 强大的多学科OCTSI领导团队+整合资源，形成临床/转化研究的协调基础设施+与社区的紧密联系以及该地区对人类研究议程的参与 我们已为有组织罪案调查组确定了三个主要目标，并提出了长远、明确和可行的方法。我们将1）创建一个专门致力于临床/转化研究学科的学术之家（OCTSI），2）培养一支训练有素的跨学科的新干部队伍， 3）创建一个“研究共享空间”--一个核心研究工具的协调基础设施，极大地扩展了研究机会，并提供了一个统一的、有效的获取途径。

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. Biomedical research institutions in Oregon are outstanding, and are prepared for a major expansion in clinical/translational investigation. We propose to form the Oregon Clinical and Translational Science Institute (OCTSI). The OCTSI will fundamentally change biomedical research to create a vibrant academic home for clinical/translational investigation. It will leverage existing strengths and remove barriers to the pace and growth of research. At the heart of the OCTSI is a robust partnership between Oregon Health & Science University (OHSU) and Kaiser Permanente's Center for Health Research (KPCHR) that brings together a strong biomedical research university and an innovative practice-based research center associated with a large patient population. The collaboration provides unique opportunities for expansion across the spectrum of human investigation, and sets the stage for major advances in human health. Transformation of clinical and translatlonal research in Oregon is enhanced by: + Robust institutional support for the OCTSI, manifest by significant administrative change as well as the commitment of substantial financial and space resources + Academic faculties at OHSU and KPCHR that fully support the OCTSI initiative and the development of a strong, multidisciplinary OCTSI leadership team + Merging of resources to form a coordinated infrastructure for clinical/translational research + Strong ties to the community and the involvement of the region in the human research agenda We have identified three major goals for the OCTSI, and propose far-reaching, explicit and feasible approaches to achieve them. We will 1) Create an academic home (the OCTSI) specifically devoted to the discipline of clinical/translational research, 2) Nurture a new cadre of highly-trained, interdisciplinary investigators through a strong, diverse educational curriculum, 3) Create a "Research Commons" - a coordinated infrastructure of core research tools that greatly expands research opportunities and provides a unified, effective means for their access.