Disseminating Breast Cancer Prevention to African American Women

描述（由申请人提供）：传播是研究过程中一个重要但被忽视的组成部分。目前，工作重点是传播通过随机试验制定和评价的干预措施;然而，还需要建立机制，向普通公众传播研究结果。AHRQ使用结构化流程准备条件的比较有效审查（CER）。虽然这些评论是为消费者编写的，但它们的覆盖面可能有限，特别是在少数种族和族裔群体中，因为传播方法不具有文化敏感性，内容也不针对特定人群。我们的小组有相当多的经验，为非洲裔美国妇女制定有针对性的乳腺癌信息，并使用文化敏感的传播策略，以达到这一人口。因此，在响应RFA-HS-10-004：创新的适应和传播AHRQ比较有效性审查，我们建议应用这种专业知识，以开发和评估一种以社区为基础的方法，传播CER关于乳腺癌预防非洲裔美国妇女。拟议研究的具体目标是：（1）根据社会人口学特征、对医学研究的信念和临床变量，评估向非裔美国妇女传播关于乳腺癌预防的CER的基于社区的方法的采用情况;（2）评估关于乳腺癌预防的证据（E）与非证据（NE）内容对心理和行为结果的影响，包括：关于乳腺癌和预防选择的知识，与社会和医疗网络中的个人沟通，以及对医学研究的不信任。我们还将确定我们的传播工作在多大程度上达到了一个样本，这是人口统计学上的代表性的非裔美国妇女在费城大都市区。本研究将分两个阶段进行，并确定通过E和NE含量以及心理和行为结果的变化来介导关系的变量。在第一阶段，我们将使用定性方法来调整现有的乳腺癌预防药物CER，以增加其与非洲裔美国妇女的相关性。在第二阶段，我们将评估的吸收社区为基础的传播论坛，并比较E和NE内容的知识，沟通有关预防和不信任的医学研究的样本中的200名非洲裔美国妇女的影响。 公共卫生相关性：尽管总体情况有所改善，但与族裔和种族群体的妇女相比，非裔美国妇女的乳腺癌发病率和死亡率仍然过高。对乳腺癌预防的行为和医疗策略缺乏认识导致非洲裔美国妇女的预后较差。我们的研究将开发和评估一种新的，以社区为基础的战略，传播有关乳腺癌预防选择的信息，以妇女在风险较差的结果。

DESCRIPTION (provided by applicant): Dissemination is an important, but neglected component of the research process. Currently, efforts focus on disseminating interventions that have been developed and evaluated through randomized trials; however, mechanisms are also needed to disseminate the results from research to the lay public. The AHRQ uses a structured process to prepare comparative effective reviews (CER) of conditions. Although these reviews are developed for consumers, they are likely to have limited reach, especially among individuals from racial and ethnic minority groups, because the dissemination methods are not culturally sensitive and the content is not targeted to specific populations. Our group has considerable experience developing targeted information about breast cancer for African American women and using culturally sensitive dissemination strategies to reach this population. Therefore, in response to RFA-HS-10-004: Innovative Adaptation and Dissemination of AHRQ Comparative Effectiveness Reviews, we propose to apply this expertise to develop and evaluate a community-based approach for disseminating CERs about breast cancer prevention to African American women. The specific aims of the proposed research are: (1) to evaluate uptake of a community-based approach for disseminating CERs about breast cancer prevention to African American women based on sociodemographic characteristics, beliefs about medical research, and clinical variables and (2) to evaluate the impact of evidential (E) versus non-evidential (NE) content about breast cancer prevention on psychological and behavioral outcomes that include: knowledge about breast cancer and prevention options, communication with individuals in their social and medical network, and distrust of medical research. We will also determine the extent to which our dissemination efforts reach a sample that is demographically representative of African American women in the Philadelphia metropolitan area. This study will be implemented in two Phases and identify variables that mediate the relationship by E and NE content and changes in psychological and behavioral outcomes. In Phase I, we will use qualitative methods to adapt an existing CER on medications for breast cancer prevention to increase its relevancy for African American women. In Phase II, we will evaluate the uptake of a community-based dissemination forum and compare the effects of E and NE content on knowledge, communication about prevention, and distrust of medical research in a sample of 200 African American women. PUBLIC HEALTH RELEVANCE: Despite overall improvements, African American women continue to experience excess rates of morbidity and mortality from breast cancer compared to women from ethnic and racial groups. Lack of awareness about behavioral and medical strategies for breast cancer prevention contributes to poorer outcomes among African American women. Our research will develop and evaluate a novel, community-based strategy for disseminating information about breast cancer prevention options to women at risk for poorer outcomes.