Derivation of clinical grade human embryonic stem cell lines for therapeutic applications

在未来，使用干细胞治疗我们目前无法治愈的疾病是可能的。这些疾病包括心脏病(英国最大的杀手)，青少年(1型)糖尿病，以及退行性神经疾病，如帕金森S和运动神经元疾病。但在我们可以在患者身上测试潜在的治疗方法之前，我们必须创造出安全的(没有感染性物质和可能的动物污染)和遗传稳定的细胞系。目前，胚胎干细胞只能用于研究。该项目旨在有效地生产符合实验室标准(称为良好制造规范，GMP)的胚胎干细胞，使其能够用于患者的治疗。这些细胞系将被保存在英国干细胞库中，并将免费提供给医学界。

In future it might be possible to use stem cells to treat diseases for which we currently have no cure. These include, heart disease (the biggest killer in the UK), Juvenile (type 1) diabetes, and degenerative neurological conditions such as Parkinson s and Motor Neurone disease. But before we can test potential therapies on patients we must create cell lines that are safe (free of infectious agents and possible animal contamination) and genetically stable. At the moment embryonic stem cells can only be used for reseach. This project aims to efficently produce embryonic stem cells to laboratory standards (called Good Manufacturing Practice, GMP) that allow them to be used for treatment of patients. The cell lines will be deposited in the UK Stem Cell Bank and will be freely available to the medical community.