CB: Pathology and Tissue Procurement Core

病理学和组织采购核心的具体目标是： 目的1维持和加强肿瘤组织和匹配血液标本的储存库， 接受治疗的中枢神经系统（CNS）肿瘤患者 得克萨斯湾D.安德森癌症中心（UTMDACC）。 目的2提供SPORE中使用的组织样本的全面组织学表征 项目，包括患者标本和动物实验肿瘤; 迅速将组织样本分发给SPORE研究人员进行分析;并提供 在SPORE内对组织切片进行研究的解释方面的专业知识 项目 目标3提供集中服务，包括生物标志物的免疫组化表征， 组织阵列设计和构建，以及肿瘤样品的原代培养，其中 适当 目标4支持一个全面的、前瞻性的交互式数据库， 在UTMDACC接受治疗或评估的CNS肿瘤患者的病理学数据。 目标5通过组织资源共享促进SPORE间的合作。

The specific objectives of the Pathology and Tissue Procurement Core are to: Objective 1 Maintain and enhance a repository of tumor tissue and matched blood specimens from patients with central nervous system (CNS) tumors receiving care at The University of Texas M. D. Anderson Cancer Center (UTMDACC). Objective 2 Provide comprehensive histologic characterization of tissue samples used in the SPORE Projects, including specimens from patients and experimental tumors in animals; expeditiously distribute tissue specimens to SPORE investigators for analysis; and provide expertise in the interpretation of studies performed on tissue sections within the SPORE Projects. Objective 3 Offer centralized services, including immunohistochemical characterization of biomarkers, tissue array design and construction, and primary culture of tumor samples where appropriate. Objective 4 Support a comprehensive, prospective interactive database with detailed clinical and pathologic data for patients with CNS tumors receiving care or evaluation at UTMDACC. Objective 5 Facilitate inter-SPORE collaborations through sharing of tissue resources.