Oregon Comparative Effectiveness Research K12 Program

描述（由申请人提供）：由于可以纠正的研究缺陷，每年投入研究的数百亿美元没有得到有效使用。比较有效性评价一致地注意到许多研究的代表性和质量问题。该提案利用OHSU在比较有效性、证据审查、初步研究、利益相关者参与和K项目成功方面的专业知识，培养比较有效性研究（CER）的未来领导者。俄勒冈比较有效性研究K - 2培训计划旨在开展循证、以患者为中心、务实的研究，1)培训临床和卫生服务CER研究人员以及学术、政府和其他机构的领导者；2)从小型的描述性研究到大型的前瞻性治疗结果评估，在以证据为基础、以患者为中心、现实世界研究的所有学科中培养学者；3)准备研究人员设计和实施利益相关者参与的，务实的，跨学科的研究项目，采用尖端的比较有效性技能。俄勒冈州CER培训计划将招收四名博士后学者，每人学习三年。学习体验将包括三个核心要素：1)比较有效性研究中的教学教育；2)广泛的经验轮换；3)一个重要的，有指导的研究经验。所有学者将参与一项比较有效性评估和一个CER项目。这个项目的轮换和实地地点包括俄勒冈循证实践中心；科学资源中心；比较效果中心；俄勒冈州医疗补助计划（俄勒冈州医疗补助计划）；社区卫生信息网络（安全网、诊所网络管理）；以及ahrq资助的俄勒冈农村实践研究网络。

DESCRIPTION (provided by applicant): Tens of billions of dollars invested in research are spent ineffectively each year because of correctable research flaws. Comparative effectiveness reviews consistently note problems in the representativeness and quality of many studies. This proposal leverages OHSU's expertise in comparative effectiveness, evidence reviews, primary research, stakeholder engagement, and K program success to train future leaders in comparative effectiveness research (CER). The Oregon Comparative Effectiveness Research K l2 Training Program aims to conduct evidence-based, patient-centered, pragmatic, research that 1) train clinical and health services CER researchers and leaders for academic, governmental, and other settings; 2) educate scholars in all the disciplines of evidence-based, patient-centered, real-world research, from small, descriptive studies to large prospective outcome evaluations of treatment; and 3) prepare researchers to design and implement stakeholder- engaged, pragmatic, and interdisciplinary research projects employing cutting-edge comparative effectiveness skills. The Oregon CER Training Program will enroll four post-doctoral Scholars, each for 3 years of study. The learning experience will feature three core elements: 1) didactic education in comparative effectiveness research; 2) broad-based experiential rotations; and 3) a significant, mentored research experience. All scholars will participate in a comparative effectiveness review and a CER project. Rotation and field sites for this program include the Oregon Evidence-based Practice Center; the Scientific Resource Center; the Comparative Effectiveness Center; CareOregon (Oregon Health Plan for Medicaid patients); the Community Health Information Network (safety net clinic network administration); and the AHRQ-funded Oregon Rural Practice-based Research Network. PUBLIC HEALTH RELEVANCE: Comparative Effectiveness (CE) reviews consistently find that a minority of studies provide meaningful information to inform real-world health care, suggesting that research could be more cost-effective. The Oregon CER K12 Program will leverage the resources and success of Oregon EPC, CTSA, and OHSU's ongoing success with K12 programs to train future leaders in CER.