Identifying neuroimaging based biomarkers for predicting clinical progression along the Lewy Body disease spectrum

路易体痴呆（LBD）包括相似但异质性组知之甚少致残性神经退行性疾病。该项目旨在将先进的神经成像技术和新颖的心理测试应用于有路易体疾病风险的患者以及已经患病的个体，以识别新的生物标志物，这些生物标志物可能解释这些疾病的症状，并有助于在早期阶段预测LBD的发展，此时它可能适合神经保护治疗。

Lewy body dementias (LBD) comprise similar but heterogenous group of poorly understood disabling neurodegenerative conditions. This project aims to apply advanced neuroimaging techniques and novel psychological testing to patients at risk of Lewy body disorders as well individuals with established disease to identify novel biomarkers that may explain symptoms of these disorders as well as help predict development of LBD at its early stages when it may be amenable to neuroprotective treatments.