Training of Arthritis Research Scientists

描述(由申请人提供)：这是对1976年首次资助的风湿学培训补助金的竞争性续签申请的修订，旨在为与风湿病问题相关的基础和临床研究领域的独立研究人员的职业生涯做好准备。符合条件的医学博士候选人已经完成了成人或儿科风湿病学的大部分临床培训，并对研究和学术生涯表现出浓厚的兴趣。符合条件的博士候选人已获得生命科学相关领域的博士学位，并寻求专注于风湿病研究。培训计划包括一系列有组织的基础科学讲座和研究会议，旨在为学员提供生物科学相关领域的概念框架，并辅之以基础、翻译和临床研究相关领域的额外必修课程工作。研究培训期包括至少两年的研究经验，同时临床承诺最少。培训项目的教师导师包括24名医学博士、博士和医学博士/博士研究员，他们的终身教职跟踪密歇根大学的教职任命，其中11人在风湿科任职，12人在其他系或科室任职，1人在风湿病和老年病学两个科任职。培训计划还得到了具有临床和研究职责(终身教职和非终身教职)的合作教员的支持，他们参加了培训计划，但不会作为受训人员的主要导师。代表的科学专长领域包括免疫学、细胞和分子生物学，以及风湿病的临床研究。风湿病学部的研究项目得到了大量的外部研究资金、超过11,000平方英尺的实验室空间以及最近更新至2011年的密歇根大学风湿病核心中心的支持。这一培训项目在风湿病及相关领域培养出了杰出的领导者。本提案中概述的师资、设施和培训计划将为扩大这些成就提供一个极好的框架。

DESCRIPTION (provided by applicant): This is a revised resubmission of a competitive renewal application for a Rheumatology Training Grant that was first funded in 1976, and that aims to prepare qualified individuals for careers as independent investigators in areas of basic and clinical research related to problems in rheumatic diseases. Eligible M.D. candidates have completed most of their clinical training in adult or pediatric Rheumatology and demonstrate a strong interest in research and in an academic career. Eligible Ph.D. candidates have received a Ph.D. degree in a relevant area of the life sciences, and seek to focus their career on rheumatic disease research. The Training Program includes a structured series of basic science lectures and research conferences designed to give trainees a conceptual framework in the relevant areas of biological science, and this is supplemented by additional required course work in relevant areas of basic, translational and clinical research. The research training period includes at least two years of research experience, with minimal concurrent clinical commitments. The faculty mentors for the Training Program include 24 M.D., Ph.D., and M.D./Ph.D. investigators with tenure track faculty appointments at the University of Michigan, eleven of whom have appointments in the Division of Rheumatology, twelve in other Departments or Divisions, and 1 in both Rheumatology and Geriatrics. The Training Program is also supported by collaborating faculty with clinical and research duties (both tenure track and non-tenure track), who participate in the Training Program, but will not serve as primary mentors for trainees. The areas of scientific expertise represented include immunology, cell and molecular biology, and clinical investigation in the rheumatic diseases. The research programs of the Division of Rheumatology are supported by substantial external research funding, by more than 11,000 square feet of laboratory space, and by the University of Michigan Rheumatic Diseases Core Center which was recently renewed through 2011. This Training Program has a strong record of producing leaders in academic rheumatology and related fields. The faculty, facilities, and training plan outlined in this proposal will provide an excellent framework for augmenting these accomplishments.