IDENTIFICATION OF TARGETS FOR POSTTRANSLATIONAL N-TERMINAL PROTEIN ARGINYLATION

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 蛋白质精氨酸化是一种鲜为人知的翻译后修饰，对心血管发育和血管生成至关重要，并可能参与其他生理系统和细胞类型的正常功能。有证据表明，许多蛋白质在体内是精氨酸化的；然而，这些蛋白质的身份尚不清楚。这项合作的目的是识别体内精氨酸化的蛋白质。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Protein arginylation is a poorly understood posstranslational modification that is essential for cardiovascular development and angiogenesis and possibly takes part in the normal functioning of other physiological systems and cell types. Evidence indicates that many proteins are arginylated in vivo; however the identity of these proteins is unknown. This collaboration is aimed to identify proteins arginylated in vivo.