PDU MICROCOMPARTMENTS

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 Pdu微区室是一种蛋白质样亚细胞结构，作为肠道沙门氏菌中1，2-丙二醇代谢的细胞器。它将几种相关的酶包裹在由几千个蛋白质亚基组成的外壳内。最近对与CO_2固定有关的微区室--羧基体的结构研究表明，羧基体中的主要壳蛋白形成六聚体，并堆积成壳的各个面。 这些子项目的目标是阐明形成Pdu微区室的蛋白质的结构。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Pdu microcompartment is a proteinaceous, subcellular structure that serves as an organelle for the metabolism of 1,2-propanediol in /Salmonella enterica/. It encapsulates several related enzymes within a shell composed of a few thousand protein subunits. Recent structural studies on the carboxysome, a related microcompartment involved in CO_2 fixation, have concluded that the major shell proteins from that microcompartment form hexamers that pack into layers comprising the facets of the shell. The goal of these subproject is to elucidate the structure of proteins that form of the Pdu microcompartment.