INVESTIGATIONS OF A NEW TYPE ENDOCRINE DISRUPTOR, TCC

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 本项目的目的是研究新型内分泌干扰物三氯卡班(TCC)对生殖功能、生殖发育的影响以及在生殖器官中诱发癌症的潜在作用。该项目的成果将解决与接触含有三氯甲烷的个人护理产品对人类的潜在不良影响有关的关切。与用啮齿动物模型收集的传统数据相比，使用非人类灵长类动物模型的研究是必要的，以提供与良性前列腺增生症(BPH)等人类疾病更相关的数据。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The objective of the project is to investigate the effects of triclocarban (TCC), a new type endocrine disruptor on reproductive function, reproductive development and the potential effects on inducing cancer in reproductive organs. The results of this project will address concerns relating to the potential effects of adverse effects in humans as a result of exposure to TCC-containing personal care products. The studies using the non-human primate animal model are necessary to provide data that is more relevant to human diseases such as benign prostatic hyperplasia (BPH), compared to traditional data collected with rodent animal models.