Community Appalachian Investigation and Research Network (CAIRN)

描述(由申请人提供)：在西弗吉尼亚州阿巴拉契亚的农村地区开发了一种新的范例，表明对科学感兴趣的训练有素的青少年可以在指导下开展基于社区的参与性研究(CBPR)。“社区阿巴拉契亚调查和研究网络(凯恩)”的合作伙伴关系是基于社区创建的健康科学和技术学院(HSTA)，这是一个州范围内的青少年科学俱乐部网络，与西弗吉尼亚大学合作建立的科学教育合作伙伴奖(SEPA)授予HSTA；西弗吉尼亚州IDEA生物医学研究卓越网络(WV-INBRE)拨款；匹兹堡大学(匹兹堡)的临床转化科学家获得临床转化科学奖(CTSA)。这一伙伴关系最近改变了HSTA计划的教育目标，将社区中积极开展CBPR也包括在内。初步可行性CBPR显示，肥胖和糖尿病在这个社区的流行比例比其他地方更大，有选择地以家庭为目标。这项建议的目标是通过凯恩延伸、扩展和实施基础设施要求，以促进社区和社区内的高质量CBPR，以改变文化生活方式行为，以改善家庭和社区健康。具体地说，我们提议建立和实施四项互动式核心活动，以补充现有资源。1)教育教育工作者计划，以促进凯恩计划多个层次之间的双向信息流，将CTSA：INBRE：SEPA与HSTA社区整合，了解CBPR和医疗保健。2.)社区研究核心，促进CBPR的组织、设计、实施和分析。这包括：关于基因、社会和环境相互作用的流行病学队列研究；关于与卫生保健有关的态度、动机和文化的结构化焦点小组研究；以及生活方式干预研究。3.)社区研究协会网络作为CBPR的一个新的社区学科，培养了该领域的科学家教育工作者，将学术界和社区结合起来，成为CBPR的科学家。4.)HSTA家庭网络提供增强的信息技术(IT)，包括临床翻译研究电子管理(em-CTR)和新的家庭健康门户，以促进双向信息流动和组织，同时保持安全和保密。这些核心设计用于连接社区和学术界，并彼此无缝交互。与广泛的教育基础设施相结合，它们将使我们能够提高CBPR的质量，并扩大可测试的假设范围。这种方法最初将应用于肥胖管理和糖尿病预防，但可以扩展到与该社区相关的任何疾病。 公共卫生相关性：阿巴拉契亚社区调查和研究网络(凯恩)的提议是对ARRA关于西弗吉尼亚州农村肥胖管理和糖尿病预防的社区参与性研究(CBPR)基础设施的倡议的回应。基础设施包括指导、教学研究设计、进行研究和实施信息技术网络。

DESCRIPTION (provided by applicant): A novel paradigm has been developed in rural Appalachia within West Virginia and shown that trained adolescents interested in science can with guidance conduct Community Based Participatory Research (CBPR). The "Community Appalachian Investigation and Research Network (CAIRN)" partnership is based on a community created Health Science and Technology Academy (HSTA), a state wide network of science clubs for adolescents built in partnership with West Virginia University, a Science Education Partnership Award (SEPA) to HSTA; a West Virginia IDeA Networks of Biomedical Research Excellence (WV- INBRE) grant; and clinical translational scientists at the University of Pittsburgh (Pitt), with its Clinical Translational Science Award (CTSA). This partnership has recently transformed educational goals of HSTA program to also include active conduct of CBPR in the community. Initial feasibility CBPR has shown a prevalence of obesity and diabetes in this community at epidemic proportions greater in this community than elsewhere, that selectively targets families. The goal of this proposal is to extend, expand, and implement infrastructure requirements through CAIRN to facilitate quality CBPR by and within the community to change cultural lifestyle behavior to improve family and community health. Specifically, we propose to build and implement four interactive core activities to complement existing resources. 1.) Educate the Educators Program to foster bi-directional flow of information between the multiple levels of the CAIRN program, integrating CTSA:INBRE:SEPA with the HSTA community about CBPR and health care. 2.) Community Study Core to foster organization, design, conduct, and analysis of CBPR. This includes: epidemiological cohort studies of gene, social and environmental interactions; structured focus group research on attitudes, motivation and culture that relate to health care; and lifestyle intervention studies. 3.) Community Research Associate Network as a new community based discipline of CBPR trained scientist educators in the field to integrate academia and the community and become CBPR scientists. 4.) HSTA Family Network to provide enhanced information technology (IT) to include electronic Management of Clinical Translation Research (eM-CTR) and a new Family Health Portal to facilitate bidirectional information flow and organization while maintaining security and confidentiality. These cores are designed to interface the community and academia, and interact seamlessly with each other. In conjunction with the extensive educational infrastructure in place they will permit us to raise the quality of CBPR, and extend the range of hypotheses that can be tested. This approach will initially be applied to obesity management and diabetes prevention but is scalable to any disease relevant to this community. PUBLIC HEALTH RELEVANCE: The Community Appalachian Investigation and Research Network (CAIRN) proposal is in response to an ARRA initiative for infrastructure for Community Based Participatory Research (CBPR) on obesity management and diabetes prevention in rural West Virginia. The infrastructure includes mentoring, teaching study design, and research conduct and implementing an information technology network.