Illumina Genome Analyzer IIx ???Next Generation??? DNA Sequencer

描述（由申请人提供）：Illumina Genome Analyzer IIx （GA II）是一款功能强大，多功能的“下一代”DNA测序仪器，具有广泛的验证应用，包括全基因组DNA测序，转录组重测序，全基因组甲基化分析，数字基因表达，ChIP-Seq等。基于使用该平台生成的数据，GA II已经发表了200多篇论文，成为当前一代测序平台中使用最广泛的工具，也是领先基因组中心的主导工具。为了支持Dana-Farber正在进行的一些需要DNA测序和序列分析的项目，John Quackenbush最近从当地一家慈善机构获得了一笔赠款，允许长期租赁/购买GA II；仪器安装于2009年3月的第二周。我们在这里寻求必要的资金，以完成购买这一工具，并在这样做时支持依赖于它的项目。

DESCRIPTION (provided by applicant): The Illumina Genome Analyzer IIx (GA II) is a robust, versatile "Next Generation" DNA sequencing instrument with a wide range of validated applications, including whole genome DNA sequencing, transcriptome resequencing, whole-genome methylation profiling, digital gene expression, ChIP-Seq, among others. With more than 200 publications based on data generated using the platform, the GA II has become the most widely used of the current generation of sequencing platforms and the dominant instrument at leading genome centers. In support of a number of ongoing projects at Dana-Farber that required DNA sequencing and sequence analysis, John Quackenbush recently received a grant from a local charity that allow for a long-term lease/purchase agreement for a GA II; the instrument was installed in the second week of March of 2009. Here we are seeking the funds necessary to complete the purchase of that instrument and in doing so to support the projects that depend upon it.