Response variability in primary auditory cortex of behaving squirrel monkey

听觉皮质表现出从时相、单峰或双峰的多种反应模式。 对每个刺激物的强直、多峰、持续的随机激发序列的反应。这个项目的目标是 觉醒时不同类型听觉皮质神经元反应变异性特征的测定 松鼠猴子。这将使我们能够评估变异性对神经元的潜在作用和影响。 编码及其对行为表现的影响，并将结果与其他反应进行比较 医疗模式。为了实现这一点，有必要获得神经和行为的同时估计 在《觉醒的动物》中的表演。将在三种情况下评估响应的可变性，在 动物以被动倾听为基线，在动物主动参与的行为中发出声音 辨别任务，以评估注意力的影响，并在接受过高度训练以评估 学习对反应变异性的表达。与其他项目一起，这些研究将 有助于建立跨感觉和运动系统的一般规则，以了解 在行为的产生中反应的可变性。

The auditory cortex exhibits a broad range of response modes spanning from phasic, single spike or binary responses to tonic, multi-spike, sustained random firing sequences per stimulus. The goal of this project is to determine the character of response variability of different types of auditory cortical neurons in the awaken squirrel monkey. This will allow us to assess the potential role and influence of variability on neuronal encoding, and its impact on behavioral performance and to compare the results to other response modalities. To achieve this, it is necessary to obtain simultaneous estimates of neural and behavioral performance in the awaken animal. Response variability will be assessed under three conditions, in the passive listening animal to serve as a baseline, in the animal actively involved in a behavioral sound discrimination task to assess attention effects, and in animals that are highly trained to assess the effects of learning on the expression of response variability. In conjunction with the other projects, these studies will contribute to establishing general rules, across sensory and motor systems, of the nature and role of response variability in the generation of behavior.