Training in Older Adult Mobility Research

描述（由申请人提供）：在最初的K24奖励期间，Pi的研究生产力和指导在深度和广度上增加和加速。随着几位学员的投入和工作，研究活动已经超越了以前的生物力学、姿势控制和功能活动的重点，进入了新的兴趣领域，包括：1)未受损和受损老年人（包括充血性心力衰竭和2型糖尿病患者）的有氧评估和干预；2)加强这些人群坚持加强身体活动的战略；3)抗阻训练的创新形式和肌肉功能改变的机制；4)残障与环境之间的接口；5)制定项目，将干预策略，特别是与降低跌倒风险有关的策略转化为社区干预策略。K24奖项为PI提供了受保护的时间，以参与广泛的地方，国家和国际指导和领导机会。PI已经能够利用他在密歇根大学和安娜堡VA GRECC广泛的培训项目基础设施的参与来扩大他的指导活动的质量和数量。继续支持K24将实现以下目标：1)进一步建立一个独立的、协作的、以患者为导向的老年人行动能力临床研究项目。2)继续Pi的临床研究领导活动，并将其作为高级导师的角色扩展到其他初级导师。3)为越来越多从事老年人活动能力临床研究的多学科培训生提供指导。4)进一步探索与流动性相关的转化研究机会，将基础科学、临床和社区应用项目联系起来。简而言之，持续的K-24支持对于PI拓宽和维持其作为导师的角色至关重要，可以为不同级别培训的多学科学员提供指导，并进一步探索与移动性相关的转化研究，从而将移动性研究中心建立为老年人临床移动性研究培训的首要项目。这项K-24奖促进的研究和培训项目不仅将推动老年人行动能力评估和增强领域的发展，而且还将为继续这一进步提供未来的领导者骨干。

DESCRIPTION (provided by applicant): During the initial K24 award period, the Pi's research productivity and mentorship increased and accelerated in depth and breadth. With the input of and work of several mentees, research activities have moved beyond a previous focus of biomechanics, postural control, and functional mobility to new areas of interest including: 1) aerobic assessments and interventions in unimpaired and impaired older adults (including those with congestive heart failure and Type 2 diabetes mellitus); 2) strategies to increase adherence to enhancing physical activity in these populations; 3) innovative forms of resistance training and the mechanisms underlying change in muscle function; 4) the interface between physical impairment and the environment; and 5) development of programs to translate intervention strategies, particularly related to fall risk reduction, into the community. The K24 award has been instrumental in giving the PI the protected time to participate in a wide range of local, national, and international mentorship and leadership opportunities. The PI has been able to leverage his participation in the extensive training program infrastructure at the University of Michigan and the Ann Arbor VA GRECC to broaden the quality and quantity of his mentorship activities. Continued K24 support will achieve the following objectives: 1) To further establish an independent and collaborative patient-oriented clinical research program in older adult mobility. 2) To continue the Pi's clinical research leadership activities and broaden his role as a senior mentor to other junior mentors. 3) To provide mentorship to a widening group of multidisciplinary trainees pursuing clinical investigation of mobility in older adults. 4) To further explore mobility-related translational research opportunities bridging basic science, clinical, and applied programs in the community. In short, continued K-24 support is critical for the PI to broaden and sustain his role as a mentor, to provide mentorship to a widening group of multidisciplinary trainees at various levels of training, and to further explore mobility-related translational research, thereby establishing the Mobility Research Center as the premier program for training in clinical mobility research for older adults. The program in research and training facilitated by this K-24 award will not only advance the field of mobility assessment and enhancement in older adults but also provide a cadre of future leaders to continue this progress.