Translational Research and Laboratory Animal Medicine Education for Veterinarians

描述(由申请人提供)：宾夕法尼亚大学(宾夕法尼亚大学)的这项研究教育补助金的目标是增加受过培训的兽医(参与者)的数量，以便为研究动物提供兽医护理，进行合作研究，并领导动物护理和使用计划。宾夕法尼亚州立大学拥有一流的生物医学研究环境，拥有医学院和兽医学院，拥有强大的学术实验动物兽医团队和出色的翻译研究项目，这使其成为这种研究教育的理想项目。我们的PI/PD和其他小组成员是宾夕法尼亚大学兽医学院病理生物学系实验动物医学部的教员，除了提供兽医和畜牧业护理和监管支持外，他们还是全面发挥作用的学术榜样。我们的行政服务小组，大学实验动物资源向副教务长报告研究，并为582个PI提供服务，使用大约1,874个有效的IACUC协议，利用每天对20多个不同物种的150,000多只动物的普查，这些动物被安置在超过240,000平方英尺的空间中。兽医学员将通过讲座和其他有组织的教学活动，以及在用于实验的多种大小动物物种的使用、生物学、护理和疾病方面的实践经验，获得知识。参与者在选定的实验室接受为期一年的指导研究培训，在非常成功的科学家的指导下使用翻译动物模型设计和执行研究。完成这一计划的兽医将有资格参加美国实验动物医学院(ACLAM)的认证。除了不同的临床医疗轮换外，还设计了特定的额外轮换，以教育参与者在实验动物资源计划、设施管理和监管支持方面的管理。这一应用程序的优势是：(1)在实验动物医学、住院医生培训、研究和指导重大学术生物医学活体服务项目方面具有丰富经验的成熟领导团队；(2)16名优秀的联合调查员研究导师，为兽医在翻译研究中提供各种机会；(3)庞大和多样化的研究动物群体，包括许多大型动物模型；(4)在实验动物和研究培训期间支持兽医的经过验证的、有指导的培训过程；(5)在兽医业务和畜牧业服务方面经验丰富的补充培训师；(6)来自专家的诊断服务和实验动物病理学方面的培训(7)陈述技能和公共演讲方面的培训和经验，以及(8)另外五名获得ACLAM和ACVIM认证的兽医，以提供临床实验动物医学的个性化并列培训。我们要求在接下来的5年里再培训3名兽医。 公共卫生相关性(由申请者提供)：兽医将接受来自R25拨款的资金培训，内容涉及实验动物医学、研究和领导动物使用计划所需的技能。这些兽医专家将通过确保研究动物的健康和福利，确保健康的动物提供最佳的科学数据，并通过使用动物进行转化研究，为公共卫生做出贡献。

DESCRIPTION (provided by applicant): The goal of this Research Education grant from the University of Pennsylvania (Penn) is to increase the number of veterinarians (Participants) trained to provide veterinary care for research animals, to perform collaborative research and to lead programs of animal care and use. Penn's premier biomedical research environment with Schools of Medicine and Veterinary Medicine, strong group of academic laboratory animal veterinarians and outstanding translational research programs makes it an ideal program for this research education. Our PI/PD and other group members form the faculty of the Division of Laboratory Animal Medicine in the Department of Pathobiology in Penn's School of Veterinary Medicine and are fully-functioning academic role models in addition to providing veterinary and husbandry care and regulatory support. Our administrative service group, University Laboratory Animal Resources reports to the Vice Provost for Research and provides services to 582 PIs with approximately 1,874 active IACUC protocols utilizing a daily census of more than 150,000 animals of more than 20 diverse species housed in more than 240,000 square feet of vivarial space. Veterinary Participants will gain knowledge through lectures and other structured didactic activities and hands-on experience in the use, biology, care and diseases of multiple large and small animal species of animals used for experimentation. Participants receive 1 year of mentored research training in selected laboratories designing and performing research using translational animal models under the guidance of highly successful scientists. Veterinarians completing this program will qualify to sit for certification by the American College of Laboratory Animal Medicine (ACLAM). In addition to varied clinical medical rotations, specific additional rotations have been designed to educate Participants in administration of laboratory animal resource programs, facility management and regulatory support. The strengths of this application are: (1) a proven leadership team with extensive experience in laboratory animal medicine, resident training, research and directing major academic biomedical vivarial service programs; (2) sixteen outstanding Co-investigator Research Mentors with varied opportunities for veterinarians in translational research; (3) large and diverse colonies of research animals including many large animal models; (4) a proven, mentored training process which supports veterinarians during laboratory animal and research training; (5) experienced supplemental trainers in vivarial business and husbandry services; (6) training in diagnostic services and the pathology of laboratory animals from experts (7) training and experience in presentation skills and public speaking and (8) five additional diverse ACLAM- and ACVIM certified veterinarians to provide individualized side-by-side training in clinical laboratory animal medicine. We request funding to train 3 additional veterinarians in the upcoming 5 years. PUBLIC HEALTH RELEVANCE (provided by applicant): Veterinarians will be trained using funds from the R25 grant in laboratory animal medicine, research and the skills needed to lead an animal use program. These veterinary specialists will contribute to public health by ensuring the health and welfare of research animals, by ensuring that healthy animals provide optimal scientific data and by performing translational research using animals.