COLUMBIA CENTER FOR HEALTH OF URBAN MINORITIES (CHUM)

该应用程序代表了我们现有的NCMHD P60卓越中心的延续和进一步发展，哥伦比亚城市少数民族健康中心（CHUM）。在CHUM前三年成功努力的基础上，我们建议将CHUM发展成为一个多学科的卓越中心，紧紧专注于心血管疾病和糖尿病的NCMHD优先领域的研究。我们计划开展三个研究项目，旨在为改善加勒比拉丁美洲少数民族的健康状况提供新的知识。 第一个项目是在控制不佳的拉丁裔糖尿病患者中进行的随机对照试验（RCT），以检查基于社区的社区卫生工作者干预在改善血糖控制方面的有效性，并将血压和胆固醇作为次要结局。 第二个项目是一项前瞻性研究，研究血糖控制不良对糖尿病患者认知功能的长期影响。 第三个项目也是一项随机对照试验，将评估以社区为基础的综合治疗性生活方式干预的有效性，其中包括关于血压控制的小组会议和动机性访谈。 该应用程序包括一个行政和研究核心，提供必要的行政、方法、统计和数据管理基础设施，以开展这三个主题相关的研究项目。 所有三个项目都将在我们的当地社区进行，在CHUM第一阶段成立的规划理事会将继续作为社区对CHUM项目的总体方向、形状和执行提供投入的正式场所。 此外，这两个RCT都建立在CHUM社区核心建立的社区伙伴关系基础上，并将社区组织作为研究的组成成员。最后，通过CHUM建立的伙伴关系和成功的努力，从其他来源获得支持，CHUM将继续为初级教师，博士后学员，研究员和本科生提供培训机会。

This application represents a continuation and further development of our existing NCMHD P60 Center of Excellence, the Columbia Center for the Health of Urban Minorities (CHUM). Building on the successful efforts of CHUM's first three years, we propose to develop CHUM into a multidisciplinary Center of excellence tightly focused on research in the NCMHD priority areas of cardiovascular disease and diabetes. We plan to conduct three research projects aimed at generating new knowledge for improving minority health among Caribbean Latinos. The first project is a randomized controlled trial (RCT) in poorly controlled Latino diabetics to examine the effectiveness of a community based Community Health Worker intervention at improving glycemic control and includes blood pressure and cholesterol as secondary outcomes. The second project is a prospective study examining the long-term consequences of poor glycemic control on cognitive function among diabetics. The third project, also an RCT, will evaluate the effectiveness of a community-based comprehensive therapeutic lifestyle intervention that includes group sessions and motivational interviewing on blood pressure control. The application includes an administrative and research core providing the requisite administrative, methodological, and statistical and data management infrastructure to carry out these three thematically linked research projects. All three projects will be conducted in our local community and the Planning Council established in the 1st phase of CHUM will continue to serve as the formal venue for community input into the overall direction, shape and execution of the CHUM project. Further, both RCTs build on the community partnerships established by CHUM's Community core and include community based organizations as integral members of the research. Lastly, through CHUM's established partnerships and successful efforts at obtaining support from other sources, CHUM will continue to provide training opportunities for junior faculty, post-doctoral trainees, fellows and undergraduate students.