Cincinnati Interdisciplinary Women's Health Research Career Training Grant

描述（由申请人提供）：这个竞争性更新申请的总体目标是维持一个有效的跨学科研究职业妇女健康研究（BIRCWH）学者计划，其任务是确定和培训辛辛那提大学（UC）医学院（COM）和辛辛那提儿童医院医疗中心（CCHMC）的初级教员。这两所机构彼此隔街相视，共享教职员工，所有CCHMC教职员工都在加州大学任职。这两个机构还共享2009年4月资助的NIH机构临床和转化科学奖（CTSA）。CTSA的学术中心是临床和转化科学与培训中心（CCTST）。我们的第一个BIRCWH奖是在妇产科颁发的，但我们培养了来自许多部门的学者，包括内科、精神病学、外科、细胞生物学和儿科。因此，为了更新，我们将把BIRCWH K12项目安置在CCTST中，BIRCWH K12学者将获得行政支持和大量的研究资源，包括研究设计、数据库管理、数据分析、试点资金、研究教育和监管支持；CCTST还运行CTSA KL2研究学者计划，并有一个非常成功的K23制备过程。我们的BIRCWH项目在培养妇女健康领域的初级教师方面建立了良好的记录。首批3名毕业的学者被聘为全职教师——1名在德克萨斯大学西南分校，1名在加州大学洛杉矶分校，1名在加州大学环境卫生系；这三家公司都是独立出资的。BIRCWH更新申请集中在6个主要领域：癌症、发育生物学、药理学/药物遗传学、生殖健康、青少年妇科和行为医学。与第一届BIRCWH一样，我们计划一次培养4名学者：2名博士和2名博士。学者将有3年的保护时间，用于指导研究和职业发展。我们召集了一批导师，他们至少有25万美元的资金；在妇女健康方面的指导记录，以及她们自己受保护的指导时间。我们还计划为职业生涯中期开始指导他人的教师设立培训导师计划。

DESCRIPTION (provided by applicant): The overall objective of this competitive renewal application is to sustain an effective Interdisciplinary Research Careers in Women's Health Research (BIRCWH) Scholars Program, whose mission is to identify and train junior faculty members within the University of Cincinnati (UC) College of Medicine (COM) and the Cincinnati Children's Hospital Medical Center (CCHMC). The 2 institutions are located across the street from each other and share faculty, with all CCHMC faculty having appointments at UC. The 2 institutions also share a common NIH Institutional Clinical and Translational Science Award (CTSA) funded in April 2009. The academic home for the CTSA is the Center for Clinical and Translational Science and Training (CCTST). Our first BIRCWH award was based in the Department of Obstetrics and Gynecology, but we trained Scholars from many departments, including Internal Medicine, Psychiatry, Surgery, Cell Biology and Pediatrics. Thus, for the renewal, we will house the BIRCWH K12 program in the CCTST, through which BIRCWH K12 scholars will have access to administrative support and a vast array of research resources, including study design, database management, data analysis, pilot funding, research education, and regulatory support; the CCTST also runs the CTSA KL2 Research Scholars program and has a very successful K23 preparation process. Our BIRCWH program has established a track record of developing junior faculty in the area of women's health. The first 3 Scholars who graduated were recruited to full-time faculty positions - 1 at University of Texas - Southwestern, 1 at UCLA, and 1 at UC's Department of Environmental Health; all 3 are independently funded. The BIRCWH renewal application focuses in 6 main areas: cancer, developmental biology, pharmacology/pharmacogenetics, reproductive health, adolescent gynecology, and behavioral medicine. As with the first BIRCWH, we plan to train 4 scholars at a time: 2 MDs and 2 PhDs. Scholars will have 3 years of protected time for mentored research and career development. We have assembled a cadre of mentors who have at least $250,000 of funding; a track record of mentoring in women's health, and their own protected time for mentorship. We also plan to institute a Mentor-in-Training program for mid- career faculty who are beginning to mentor others. PUBLIC HEALTH RELEVANCE: Nationally, there is a major unmet need for training clinical and basic science trainees and faculty to conduct research in women's health. Through mentored research and coursework, the Cincinnati BIRCWH K12 program will continue to train leaders in women's health research.