NEI Mentored Clincial Scientist Development Program Award (K12)

描述（由申请人提供）：这是一个机构培训补助金的建议，以教育下一代的临床医生，科学家在眼科学术职位。38年来，杜克大学眼科中心（DUEC）一直是培养学术眼科医生的国家领导者。这些受训人员的最早一代现在在全国和国外的学术医疗中心担任许多领导职务。他们有作为院长，系主任和教师的角色，并作为导师的院士。我们建议通过一个旨在提供必要的指导，资源和教学，以生产临床科学家在眼科学术职位的强化计划继续这一传统。我们计划每年挑选两名实习生，在他们完成眼科或病理学实习后，进行为期3年的密集培训。 一个教育计划，将导致独立的同行评审赠款资金和教师的立场 在一个学术机构。学员将接受强化教学课程， 由杜克大学的资深教师提供密切的指导。每名受训人员将接受以下强制性培训： 临床研究、遗传学、统计学、科学写作、拨款准备、伦理学和 负责任地进行研究。每位学员将参与重要的原创性研究， 学习基本技能，发展成功和独立的学术生涯。额外 每个受训人员的课程将由项目主任和首席导师量身定制 根据选定的主要研究方向和他/她的技能，背景和职业目标。我们 提出五个主要研究方向：（1）转化医学和临床试验，（2）临床和 （3）眼科基因组学和蛋白质组学，（4）眼科病理学，（5） 成果和卫生政策。由于国际眼科病理学家短缺， 试图招募和适当的个人从事涉及使用眼组织的研究事业 来自患者和实验模型。 公共卫生相关性：

DESCRIPTION (provided by applicant): This is an institutional training grant proposal to educate the next generation of clinician-scientists for academic positions in Ophthalmology. For over 38 years, the Duke University Eye Center (DUEC) has been a national leader in training academic Ophthalmologists. The earliest generations of these trainees now serve in numerous leadership positions in academic medical centers across the country and abroad. They have roles as Deans, Department Chairs, and faculty members and serve as mentors for academicians. We propose to continue this tradition through an intensive program designed to provide the guidance, resources, and didactic teaching necessary to produce clinician-scientists for academic positions in Ophthalmology. We plan to select two trainees each year after their completion of a residency in Ophthalmology or Pathology for an intense 3 year educational program that will lead to independent peer-reviewed grant funding and a faculty position in an academic institution. The trainees will undergo an intensive didactic curriculum combined with a close mentorship by senior faculty at Duke University. Each trainee will receive mandatory training in areas of clinical research, genetics, statistics, scientific writing, grant preparation, ethics, and the responsible conduct of research. Each trainee will participate in significant original research and learn the essential skills to develop a successful and independent academic career. Additional aspects of the curriculum of each trainee will be tailored by the program director and lead mentor based upon the selected primary research track and his/her skills, background and career goals. We propose five primary research tracks: (1) translational medicine and clinical trials, (2) clinics and bedside to the bench, (3) Ophthalmic genomics and proteomics, (4) ophthalmic pathology, (5) outcomes and health policy. Because of an international shortage of Ophthalmic Pathologists we will attempt to recruit and appropriate individuals for a research career involving the use of ocular tissues derived from patients and experimental models. PUBLIC HEALTH RELEVANCE: