Impact of somatic versus dendritic inhibition on neuronal output

大脑是由数十亿个神经元组成的，它们以复杂的网络连接在一起。这些神经元有两种主要类型——兴奋性和抑制性——它们在平衡中工作。过多的兴奋会使大脑癫痫，过多的抑制会使我们陷入昏迷。该建议侧重于特定抑制细胞类型在调节脑功能中的作用，并与癫痫，精神分裂症和抑郁症等一系列神经系统疾病相关。

The brain is made up of literally billions of neurons connected in complex networks. These neurons come in two primary flavors - excitatory and inhibitory - which work in balance. Too much excitation and the brain becomes epileptic, too much inhibitory and we go into a coma. This proposal focuses on the role of specific inhibitory cell types in regulating brain function, and has relevant to a range of neurological disorders from epilepsy, to schizophrenia to depression.