Role of calcium-activated potassium channels in neuronal excitability, synaptic plasticity and sensory processing

钙激活钾通道在神经元兴奋性、突触可塑性和感觉处理中的作用

• 批准号: nhmrc : 1125915
• 负责人: Prof Greg Stuart
• 金额: $ 41.83万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-calcium-activated-sensory-processing/947695
• 关键词: Role; calcium; activated; potassium; channels

Disturbances in brain function, as occur in diseases such as epilepsy and schizophrenia, are associated with abnormal electrical activity. This electrical activity leads to increases in calcium inside nerve cells. In this project we plan to investigate how changes in calcium inside nerve cells regulates electrical activity, and how this impacts on the capacity of the brain to process and learn new information.

大脑功能障碍，如癫痫和精神分裂症等疾病，与异常的电活动有关。这种电活动导致神经细胞内钙的增加。在这个项目中，我们计划研究神经细胞内钙离子的变化如何调节电活动，以及这如何影响大脑处理和学习新信息的能力。