Investigating action potential initiation and propagation in neurons using voltage-sensitive dyes

使用电压敏感染料研究神经元动作电位的启动和传播

• 批准号: nhmrc : 525460
• 负责人: Prof Greg Stuart
• 金额: $ 21.14万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/investigating-action-potential-sensitive-dyes/97627
• 关键词: Investigating; action; potential; initiation; propagation

Nerve impulses, or action potentials, are the fundamental electrical signals used by the nervous system for communication. Critical to an understanding of neuronal function is the knowledge of where these events are initiated and how they propagate. Furthermore, this knowledge is required for understanding what goes wrong under conditions where there is a disturbance in neuronal communication, as occurs in many neurological disorders such as multiple sclerosis and epilepsy.

神经冲动或动作电位是神经系统用于通信的基本电信号。了解神经元功能的关键是了解这些事件在哪里开始以及如何传播。此外，这种知识是理解在神经元通信干扰的情况下出现问题所必需的，如在许多神经系统疾病中发生的，如多发性硬化症和癫痫。