2011 Carbohydrates Gordon Research Conference

描述（由申请人提供）：本提案要求部分支持将于2011年6月19日至24日在缅因州科尔比学院举行的关于碳水化合物的戈登研究会议。本次会议的广泛和长期目标是汇集来自一系列化学和生化学科的糖科学家，讨论未发表的研究并确定该领域的重要问题。本次会议的具体目标是：1)汇集研究碳水化合物化学和生物化学的知名和年轻研究人员，包括学生和博士后学者，并尽一切努力将女性、少数民族和残疾人纳入其中；2)介绍碳水化合物合成、计算和分析工具的现状，重点通过诊断、疫苗和其他治疗方法的开发等领域的应用实例以及学术界的前沿实例说明它们的能力和局限性；3)突出新兴研究领域，并在合成化学家、分析化学家、计算化学家/生物学家/生物信息学家和化学生物学家之间建立跨学科合作，以最好地解决我们理解基于碳水化合物相互作用的结构、功能和治疗和诊断干预的障碍。这一应用的意义在于，这次戈登研究会议将提供一个独特的国际论坛，汇集具有一系列化学和生物学背景的科学家，他们对碳水化合物化学和生物学感兴趣。该应用与健康的关系在于，所产生的讨论将有助于确定与基础糖科学相关的重要问题，以及干预碳水化合物介导的疾病过程（如宿主-病原体相互作用和癌症）所需的治疗策略的发展。

DESCRIPTION (provided by applicant): This proposal requests partial support for a meeting on Carbohydrates as a Gordon Research Conference to be held at Colby College in Maine from June 19-24, 2011. The broad and long-term goal of this conference is to bring together glycoscientists from a range of chemical and biochemical disciplines to discuss unpublished research and define important questions in the field. The specific aims of this meeting will be to 1) bring together established and young investigators, including students and postdoctoral scholars, with every effort made to include women, minorities and the disabled, who work on the chemistry and biochemistry of carbohydrates; 2) present the current state of carbohydrate synthetic, computational, and analytical tools with an emphasis on illustrating their abilities and limitations through applied examples in areas such as the development of diagnostics, vaccines, and other therapeutics, as well as with cutting-edge examples from academia; and 3) highlight emerging research areas and build interdisciplinary collaborations between synthetic chemists, analytical chemists, computational chemists/biologists/bioinformaticists, and chemical biologists to best tackle the obstacles to our understanding of the structure of, functions of, and therapeutic and diagnostic interventions based on carbohydrate interactions. The significance of this application is that this Gordon Research Conference will provide a unique international forum to bring together scientists with a range of chemistry as well as biology backgrounds with interests in carbohydrate chemistry and biology. The health relatedness of this application is that the discussions generated will help define the important questions relating to basic glycoscience and also those required for the development of therapeutic strategies needed to intervene in carbohydrate-mediated disease processes such as host-pathogen interactions and cancer. PUBLIC HEALTH RELEVANCE (provided by applicant): The Gordon Research Conference on Carbohydrates will bring together established and young investigators, including students and postdoctoral scholars, with every effort made to include women, minorities and the disabled, who work on the chemistry and biochemistry of carbohydrates to present the current state of carbohydrate synthetic, computational, and analytical tools with an emphasis on illustrating their abilities and limitations through applied examples in areas such as the development of diagnostics, vaccines, and other therapeutics, as well as with cutting-edge examples from academia. In addition, the conference will highlight emerging research areas and build interdisciplinary collaborations between synthetic chemists, analytical chemists, computational chemists/biologists/bioinformaticists, and chemical biologists to best tackle the obstacles to our understanding of the structure of, functions of, and therapeutic and diagnostic interventions based on carbohydrate interactions.