Histiocyte Society Annual Meeting to be Held in Boston

描述（由申请方提供）：组织细胞病是单核吞噬细胞系统的罕见非恶性疾病。许多这些疾病的病理生理学是未知的，并且在广泛传播和潜在致命形式的情况下，迄今为止的治疗是非常有效的，有时是高毒性的。组织细胞病符合孤儿病的认定标准。组织细胞学会成立于26年前，是一个由临床医生和科学家组成的独特国际组织，致力于扩大对这些疾病的了解并改善治疗结果。活动的一个主要焦点是在世界各地改变地点的年会。科学议程包括特邀演讲者关于组织细胞疾病生物学的最新发展，以及与巨噬细胞和树突细胞的发展有关的更基本的血液学和免疫学主题，以及免疫稳态机制的演讲。该计划还设有几个平台会议和一个由社会教育委员会评分的选定摘要的主持海报展示。此外，会议还允许社会执行委员会，教育和科学委员会，LCH和HLH疾病兴趣小组，以及管理社会赞助的临床试验的临床研究小组和数据安全监测委员会的面对面会议。 公共卫生相关性：组织细胞疾病，虽然个别罕见，作为一个群体代表了一个重大的负担，卫生保健系统由于管理儿童与这种疾病的复杂性和成本。患有组织细胞增多症的成年患者尤其得不到充分的服务。对儿童有效的治疗对老年患者往往毒性太大。组织细胞学会年会是聚集来自世界各地的医疗从业者共同努力的唯一机会，以促进知识，从而改善这些患者的治疗结果。

DESCRIPTION (provided by applicant): The Histiocytoses are rare non-malignant disorders of the mononuclear phagocytic system. The pathophysiology of many of these diseases is unknown and, in the case of the widely- disseminated and potentially fatal forms, treatments to date have been variably effective and sometimes highly toxic. Histiocytoses meet criteria for designation as orphan diseases. The Histiocyte Society, founded 26 years ago, is the unique international organization of clinicians and scientists focused on expanding knowledge about these diseases and improving treatment outcomes. A major focus of activities is the annual meeting which changes venues around the world. The scientific agenda includes presentations by invited speakers regarding the most recent developments in the biology of histiocytic disorders, as well as topics in more basic hematology and immunology related to the development of macrophages and dendritic cells, and mechanisms of immune homeostasis. The program also has several platform sessions and a moderated poster presentation of selected abstracts which have been scored by the Educational Committee of the society. Additionally, the meeting allows for face to face meetings of the Executive Board of the society, the Educational and Scientific committees, LCH and HLH Disease Interest Groups, and clinical study groups that manage the society-sponsored clinical trials, and the Data Safety Monitoring Board. PUBLIC HEALTH RELEVANCE: The Histiocytic Disorders, while individually rare, as a group represent a significant burden to the health care system due to the complexity and cost of managing children with such disorders. Adult patients with histiocytosis are particularly underserved. Treatments which are effective in children are often too toxic for older patients. The Histiocyte Society annual meetings are the only opportunity to gather medical practitioners from around the world working together to advance knowledge which leads to improved treatment outcomes in these patients.