Admin Core

N2B。行政核心组织和人员 行政核心由Lauffenburger教授和Yaffe教授、洛里Spindler教授和KI行政助理主任（Cynthia Quense）组成;后两者在KI和MIT使用的系统下运作。Spindler女士与Quense女士、Lauffenburger教授和Yaffe教授协商，管理TCNC的日常细节和运作。这里展示了一个组织结构图。TCNC的总体科学和技术指导由主任/联合主任与外部咨询委员会、项目/核心领导人和指导委员会密切合作提供。指导委员会制定业务技术计划和决策，例如选择PI，试点项目，研究生研究员和科学顾问委员会 成员目前，该指导委员会由Richard Hynes、Leona Samson和布鲁斯蒂多尔（也负责教育/外联核心）以及Lauffenburger和Yaffe教授沿着组成。委员会每年至少举行两次会议，必要时还通过电子邮件举行会议。麻省理工学院科赫综合癌症研究所所长泰勒·杰克斯是项目1的成员，并将他的机构知识借给了该项目。 行政核心的总体使命是监督和协调麻省理工学院CCSB的行政和财政方面。该单位的具体职责如下：（i）提供财政管理和预算监督;（ii）为CCSB的所有活动提供关键的行政支持和相关的会议规划;（iii）建立促进和跟踪教育和外联计划的具体机制;（iv）协助共同主任支持TCNC的科学目标。麻省理工学院KI管理着一个由Quense女士领导的中央管理机构。所有KI奖都由总部办公室管理，该办公室还管理KI经营的所有核心设施。一位高级财务管理人员和她的工作人员管理着大约2500万美元的研究资金，以及奖学金和其他研究所范围内对癌症研究的支持（安娜富勒基金，科赫研究基金，路德维希研究基金等）。和十二个共享的核心设施，为多个用户都在KI和其他地方在麻省理工学院。分配给每个PI的财务人员授权并批准实验室人员发起的电子报价，确保符合OMB通函A-21和成本会计标准。他们还负责核对账目，编制每月预算预测，核准和处理差旅费凭单，核准付款发票。KI助理主任和高级财务管理员项目主任/主要研究者（最后，第一，中间）：Lauffenburger，道格拉斯A都是大学研究管理人员和癌症中心管理员论坛的国家理事会的成员，并参加年度会议和专门的培训课程，以保持对法规和合规性问题的评估。他们与研究所的采购办公室、主计长的会计办公室和赞助方案办公室密切合作，确保对所有授标进行适当的财务管理。此外，他们还与环境健康和安全办公室、比较医学司和使用人体作为实验对象委员会合作，以确保遵守规定。作为项目管理员，Spindler女士负责监督 节目她是主任/联合主任、项目负责人和科赫研究所中央工作人员之间的桥梁，并参与协调项目成员实验室之间的活动。她将继续负责协调所有与CCSB有关的活动、指导委员会、联合小组会议、每月系列研讨会和教育/外联活动。Spindler女士的办公室位于KI，确保所有业务的有效协调，包括财务管理，法规遵从和人力资源。KI财务人员的Jack Cimino主要负责我们CCSB计划的日常财务管理。此外，他还负责核对与该方案有关的账户，编制季度预算预测，批准和处理差旅费凭单和付款发票。

N2B. ADMINISTRATIVE CORE ORGANIZATION AND PERSONNEL The Administrative Core consists of the Profs Lauffenburger and Yaffe, Lori Spindler, and the KI Assistant Director of Administration (Cynthia Quense); the latter two operate under the systems used by the KI and MIT. Ms Spindler, in consultation with Ms Quense, Profs Lauffenburger and Yaffe, manages the day-to-day details and functioning of the TCNC. An organizational chart is illustrated here. Overall scientific and technical direction of the TCNC is provided by the Director/Co-Director in close collaboration with the External Advisory Board, the Project/Core Leaders and the Steering Committee. The Steering Committee makes operational technical plans and decisions, such as the selection of PIs, Pilot Projects, Graduate Student Fellows, and Scientific Advisory Board members. At the present time, this Steering Committee comprises Richard Hynes, Leona Samson, and Bruce Tidor (who is also in charge of the Education/Outreach Core) along with Profs Lauffenburger and Yaffe. It meets in person at least twice per year, and additionally via email when useful. The Director of the MIT Koch Institute for Integrative Cancer Research, Tyler Jacks, is a Member of Project 1 and lends his institutional knowledge to the program. The overall mission of the Administrative Core is to provide oversight and coordination on administrative and fiscal aspects of the MIT CCSB. The specific responsibilities of this unit are as follows: (i) provide fiscal management and budgetary oversight; (ii) provide key administrative support, and associated meeting planning, for all CCSB activities; (iii) establish specific mechanisms to facilitate and track Education and Outreach programs; (iv) assist the co-directors in support of the scientific aims of the TCNC. The MIT KI runs a centralized administration headed by Ms Quense. All KI awards are administered by the headquarters office, which also administers all the core facilities run by the KI. A Senior Financial Administrator and her staff administer a research volume of approximately $25 million as well as fellowships and other Institute-wide support of cancer research (Anna Fuller Fund, Koch Research Funds, Ludwig Research Funds, etc.) and twelve shared core facilities for multiple users both within the KI and elsewhere at MIT. Financial staff, assigned to each PI, authorizes and approve electronic requisitions initiated by laboratory personnel, ensuring compliance with OMB Circular A-21 and the Cost Accounting Standards. They are also responsible for reconciling accounts and preparing monthly budget projections, approving and processing travel expense vouchers, and approving invoices for payment. The KI Assistant Director and Senior Financial Administrator Program Director/Principal Investigator (Last, First, Middle): Lauffenburger, Douglas A are both members of the National Council of University Research Administrators and the Cancer Center Administrator's Forum and participate in annual meetings and specialized training courses to remain appraised of regulation and compliance issues. They work closely with the Institute's Procurement Office, the Controller's Accounting Office and the Office of Sponsored Programs to ensure appropriate financial management of all awards. In addition, they work in conjunction with the Environmental Health and Safety Office, the Division of Comparative Medicine and the Committee on the Use of Humans as Experimental Subjects to ensure compliance. As Program Administrator, Ms Spindler oversees day-to-day management of the program. She serves as a conduit between the Director/Co-Director, Project Leaders and the centralized Koch Institute staff, and is involved in coordinating activities among Project member laboratories. She will continue to be responsible for coordinating all CCSB-related activities, steering committees, joint group meetings, monthly seminar series and the Education/Outreach activities. Ms Spindler's office is located in the KI, ensuring efficient coordination of all operations including financial management, regulatory compliance and human resources. Jack Cimino of the KI financial staff holds primary responsibility for the day-to-day financial management of our CCSB program. In addition, he is responsible for reconciling the accounts associated with this program and preparing quarterly budget projections, approving and processing travel expense vouchers and invoices for payment.