PPP

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 波多黎各临床和转化研究联盟(PRCTRC)的多学科和转化试点项目计划(MT3P)是促进基础科学知识转化到床边或社区的努力的关键组成部分，这是转化研究路线图的[关键]原则。新的少数民族科学家的发展非常需要经过适当的培训和 他们将拥有相似的文化背景，从而更好地了解和了解少数群体健康方面的挑战和局限。 拟议的多学科和转化性试点项目计划旨在促进从单一研究人员基础科学方法向转化性方法过渡的可取方面，并创建一种“团队”方法来研究少数群体中普遍存在的健康问题。该计划的总体目标是帮助推进影响少数群体的健康差距的临床和转化性研究，并支持开发新的研究人员或新的研究领域。我们的具体目标是为涉及多学科研究团队的初步研究提供研究支持，这些研究团队将基础和临床科学家联系起来，专注于研究在少数族裔和西班牙裔人口中特别普遍的健康差距。波多黎各临床和转化性研究联盟(PRCTRC)处于有利地位，能够实现这些目标，因为它可以接触少数族裔患者和医疗保健专业人员，以及将参与这一倡议的合作机构之间已经存在的专业知识和协同作用。 为实现拟议的目标和目标，我们将实现以下具体目标： 具体目标1.为初步数据的产生提供支持，这些数据将对制定关于少数群体健康差距的翻译和临床研究项目至关重要。 具体目标2.促进临床和转化性研究新技术和新方法的发展 具体目标3.提高初级和资深研究人员在编制涉及多学科合作的竞争性提案方面的专门知识，将基础科学成果转化为临床应用，并研究拉美裔社区健康差距中的重要问题。 试点项目计划将重点放在PRCTRC的科学领域：癌症、心血管疾病、艾滋病毒、神经科学。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The Multidisciplinary and Translational Pilot Project Program (MT3P) of the Puerto Rico Clinical and Translational Research Consortium (PRCTRC) is a key component in the efforts to promote translation of basic science knowledge to the bedside or the community, [critical] tenets of the translational research roadmap. There is a great need for the development of new minority scientists with proper training and skills, scientists that will have the advantage of similar cultural backgrounds and thus greater access and insight into the challenges and limitations of health in minority populations. The proposed Multidisciplinary and Translational Pilot Project Program is designed to promote desirable aspects in the transition from single investigator basic science approach to translational approaches, and the creation of a "team" approach to the study of prevalent health problems in minority populations. The overall goal of the program is to help advance clinical and translational research in the health disparities affecting minorities and support the development of new investigators or new areas of research. Our specific objective is to provide research support for preliminary studies that involve multidisciplinary research teams linking basic and clinical scientists, focused in the study of health disparities that are particularly prevalent in minority and Hispanic populations. The Puerto Rico Clinical and Translational Research Consortium (PRCTRC) is well positioned to accomplish these goals, given its access to minority patients and health care professionals and the expertise and synergy that already exists between the collaborating institutions that will be participating in this initiative. To accomplish the proposed goals and objectives we will pursue the following specific aims: Specific AIM 1. To provide support for the generation of preliminary data that will be critical in the development of translational and clinical research projects in health disparities within minority populations. Specific AIM 2. To promote the development of new technologies and methodologies in clinical and translational research Specific AIM 3. To increase the expertise of junior and established investigators in the preparation of competitive proposals that involve multidisciplinary collaborations, translate basic science findings to clinical applications and study important issues in health disparities in Hispanic communities. The Pilot Project Program will emphasis the PRCTRC's scientific areas: cancer, cardiovascular, HIV, neuroscience.