Boston University Clinical and Translational Science Award (CTSA) Program UL1

波士顿大学提议创建一个临床和转化科学研究所，即BU-BRIDGE研究所，它将整合、连接和扩展我们目前的研究和大学项目，从而为下一代临床和转化研究人员提供一个学术和智力的家园。研究院将围绕五大事业部进行组织：1}转化科学孵化器；2)信息;3)加强临床研究；4)社区活动；（五）科研教育与培训。这五个部门专门设计用于支持从实验室或床边开始的双向开发和思想转化，从而产生新的相关工具，以改善健康，医疗保健和交付。BU- bridge将实现五个具体目标：1)协调现有的和确定现有的BU科学家之间有潜力发展成多学科转化项目的新合作，并促进BU“一站式购物”计划，以创造知识产权和转化科学思想的商业化；2)通过试点资助网络，支持现有和新的转化项目和核心的进一步发展。3)为新的和现有的临床和转化研究项目提供扩展和丰富的基于bu - bridge的机构支持菜单，包括改进的、用户友好的医学信息系统（仓库），将研究从我们的GCRC扩展到社区人群，提供伦理、监管问题、研究设计的综合方法；4)为临床医生和临床和基础科学家之间的双向思想交流提供渠道，使社区更充分地参与研究过程，包括确定调查的优先事项、设计研究、确保合乎道德的研究行为和根据研究结果实施最佳做法；5)作为培养下一代研究人员的中心，使用适当的工具将基础科学转化为临床研究。新学院是取代传统院系的跨大学实体。它整合了多个重点大学项目，包括国家新兴传染病实验室、弗雷明汉心脏研究、波士顿大学技术开发商业化组合办公室、生物医学工程和生物信息系、萨金特联合健康专业人员学院、波士顿健康网络、波士顿医疗中心和VA医院，这些项目支持大学对转化研究的广泛承诺。CTSA奖将提供资源，通过利用现有优势创造一个环境，将新的想法、教员、学员和大学项目联系起来，加速医学科学的创新，从而实现研究所的转型。BU-BRIDGE的使命与公共卫生有关，因为它将加强地方和国家社区成员可获得的保健做法的发展。

Boston University proposes to create a Clinical and Translational Science Institute, the BU-BRIDGE Institute, that will integrate, connect and expand our current research and university programs and, thereby, provide an academic and intellectual home for the next generation of clinical and translational investigators. The Institute will be organized around five Divisions: 1} Translational Science Incubator; 2) Informatics; 3) Clinical Research Enhancements; 4) Community Engagements; and 5) Research Education and Training. These five divisions are specifically designed to support the bi-directional development and translation of ideas that begin in the laboratory or bedside move seamlessly back and forth to result in new relevant tools to improve health, health care and delivery. The BU-BRIDGE will accomplish five specific aims: 1) Coordinate existing and identify new collaborations among existing BU scientists with the potential to develop into multidisciplinary translational programs, and facilitate the BU "one stop shopping" program for creating intellectual property and commercialization of translational scientific ideas; 2) Support the further development of existing and the creation of new translational programs and cores through a network of pilot grants. 3) Provide new and existing Clinical and Translational research programs with an expanded and enriched menu of BU-BRIDGE-based institutional support, including an improved, user friendly medical informatics system (warehouse), expansion of research from our GCRC into community populations, provide an integrated approach to ethics, regulatory issues, study design, analysis and implementation of health interventions 4) Provide the conduit for bidirectional flow of ideas between clinicians and clinical and basic scientists to more fully engage the community in the research process including setting priorities for investigation, designing studies, ensuring ethical research conduct and implementing best practices based on study results; 5) Serve as the Center for training the next generation of investigators with the proper tools to translate basic science into clinical research. The new institute is cross University entity that supercedes traditional departments and schools. It encorporates multiple key university programs including the National Emerging Infectious Diseases Laboratory, Framingham Heart Study, Boston University Office of Technology Development Commercialization portfolio, Departments of Biomedical Engineering and Bioinformatics, Sargent College of Allied Heath Professionals, the Boston Health Net, Boston Medical Center and VA Hospitals that support the university wide commitment for a home for translational research. The CTSA award will provide the resources to transform the institute by leveraging existing strengths to create an environment that will link new ideas, faculty, trainees and university programs to speed innovations in medical science. The mission of the BU-BRIDGE is relevant to the public health as it will enhance the development of healthcare practices available to members of the local and national communities.