Cancer Prevention Training in Nutrition, Exercise & Genetics

描述（由申请人提供）：癌症预防领域的跨学科性质需要广泛的研究技能。在过去的4年里，我们成功地实施了R25 T跨学科培训计划，重点是人类营养，运动，遗传学和代谢途径在癌症易感性和预防中的相互关系。该培训方案的目标是：（1）继续制定和实施新的课程和相关的新课程，为流行病学、营养学、遗传学和分子与细胞生物学的博士前和博士后研究员提供第二领域的跨学科培训，以及（2）在进行多学科癌症预防研究方面提供广泛的研究经验，重点是人类营养，遗传学和代谢途径。我们建议培养5名博士前研究员和3名博士后研究员。正式的课程和学位将由华盛顿大学的四个参与项目提供：流行病学，营养科学，公共卫生遗传学和分子与细胞生物学。每个学员将完成由这个R25 T在他/她的博士领域以外的第二领域开发的新课程。该课程是基于现有的课程加上4个新的课程开发的R25 T，以填补跨学科培训的空白。学员将在弗雷德哈钦森癌症研究中心的三个单位内获得癌症预防研究的经验：癌症预防，流行病学和人类生物学。每个研究员将有至少两个来自不同学科的研究导师。一个由参与方案的领导人组成的咨询委员会将挑选受训人员，监测他们的进展情况，并向方案主任提出建议。完成该计划的学员将拥有教学和研究经验，使他们能够成为多学科癌症预防研究项目的知识渊博的研究人员。

DESCRIPTION (provided by applicant): The interdisciplinary nature of the field of cancer prevention requires a broad spectrum of research skills. In the past 4 years, we have successfully implemented an R25T interdisciplinary training program with emphasis on the interrelationships of human nutrition, exercise, genetics and metabolic pathways in cancer susceptibility and prevention. The objectives of this training program are: (1) To continue to develop and implement a new curriculum and associated new courses to provide trans-disciplinary training in a secondary area to pre- and post-doctoral fellows in Epidemiology, Nutrition, Genetics and Molecular and Cellular Biology, and (2) To provide extensive research experience in the conduct of multidisciplinary cancer prevention research, with emphasis on human nutrition, genetics and metabolic pathways. We propose to train 5 pre- and 3 post-doctoral fellows. Formal coursework and degrees will be given by four participating programs of the University of Washington: Epidemiology, Nutritional Sciences, Public Health Genetics and Molecular and Cellular Biology. Each trainee will complete a new curriculum developed by this R25T in a secondary area outside his/her PhD area. This curriculum is based on existing courses plus 4 new courses developed by this R25T to fill gaps in trans-disciplinary training. Trainees will gain experience in cancer prevention research within three units of the Fred Hutchinson Cancer Research Center: Cancer Prevention, Epidemiology, and Human Biology. Each fellow will have at least two research mentors from different disciplines. An Advisory Committee composed of leaders of the participating programs will select trainees, monitor their progress and advise the Program Director. Trainees who complete this program will have the didactic and research experience to allow them to be knowledgeable investigators on multidisciplinary cancer prevention research projects.