COBRE: UAF: ADMINISTRATIVE CORE A

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 行政核心的具体目标是： 1. 提供行政领导和监督，包括财政管理和问责制。 2. 领导CANHR的科学工作，提供指导和知识氛围，这将增加CANHR调查人员提交的提案的数量和成功率。 3. 促进跨文化交流和使用社区为基础的研究（CBPR）的方法，无论是内部和之间CANHR和阿拉斯加原住民村庄，我们的合作伙伴区域卫生公司，和阿拉斯加原住民研究小组在阿拉斯加。 4. 根据基于文化的CBPR，IRB要求和部落健康公司道德准则的原则，领导和协调现场工作。 5. 提供持续的形成性和总结性评估。 6. 完成CANHR长期供资的战略规划进程。 通过最初的COBRE的支持，CANHR现在处于高水平的知名度;国家和原住民社区希望该大学将与阿拉斯加原住民社区保持长期的生物医学和健康研究承诺。我们通过与土著社区真正的CBPR伙伴关系合作，赢得了这种尊重。鉴于研究人员利用这些社区的历史以及未能分享结果，CANHR为文化上适当的长期研究提供了一个有效的模式。CANHR研究项目是转化研究的基石，以改善土著社区的健康状况，减少健康差距，并推广到世界各地的其他土著和少数群体。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Specific Aims for the Administrative Core are to: 1. Provide administrative leadership and oversight, including fiscal management and accountability. 2. Lead the scientific work of the CANHR, providing mentorship and an intellectual climate that will increase the number and success rate of proposals submitted by CANHR investigators. 3. Facilitate cross-cultural communication and use of the Community-Based Participatory Research (CBPR) approach both within and between CANHR and Alaska Native villages, our partnering regional health corporation, and Alaska Native research groups in Alaska. 4. Provide leadership and coordination for field work in accordance with the principles of a culturally-based CBPR, IRB requirements, and tribal health corporation ethical guidelines. 5. Provide ongoing formative and summative evaluation. 6. Complete a strategic planning process for the long-term funding of CANHR. Through the support of the original COBRE, CANHR is now at a high level of visibility; the State and Native communities expect that the University will sustain a long-term commitment to biomedical and health research with Alaska Native communities. We have earned this respect by working collaboratively, in true CBPR partnership, with Native communities. Given the history of exploitation of these communities by researchers and failure to share results, CANHR provides an effective model for culturally appropriate and long-term research. CANHR research projects serve as building blocks for translational research to improve health and reduce health disparities in indigenous communities, with generalizability to other indigenous and minority groups worldwide.