Animal Care Core

精确的表型鉴定在很大程度上取决于动物受试者的质量。稳定住房和畜牧业 将可能扭曲表型结果的外部因素的影响降至最低。此外，老鼠 提交给马萨诸塞州大学MMPC，与来自不同微生物来源的队列共享空间。他们，作为 与寄居在常驻群体中的小鼠一样，必须保护小鼠免受外来物种的潜在交叉感染 探员们。爱护动物中心在杰拉尔德·西尔弗曼博士担任核心主任的监督下运作， 他负责监督加州大学马萨诸塞州医学院的动物护理设施。爱护动物中心提供设施 以及在以下具体目标下与这些优先事项相关的服务：(1)提供稳定、 为老鼠提供生物围栏住房、饲养和保健(2)提供专用住房 (LRB的PODL-124)和现场表型程序，(3)评估每个 并向中心主任提供关于结果的解释和建议，以及(4) 由中心主任酌情向表型鉴定服务的用户提供结果和建议 关于提交的小鼠的健康状况。爱护动物中心的目标是支持 UMASS MMPC与动物护理和小鼠表型质量相关的问题。

Precise phenotyping depends significantly on the quality of animal subjects. Stable housing and husbandry minimize the influence of exogenous factors that could distort phenotyping results. Additionally, mice submitted to the UMass MMPC share space with cohorts from microbiologically diverse sources. They, as well as mice housed in resident colonies, must be protected against potential cross-infection by adventitious agents. The Animal Care Core operates under the supervision of Dr. Jerald Silverman as the Core Director, who oversees the animal care facility of UMass Medical School. The Animal Care Core provides facilities and services relevant to these priorities under the following specific aims: (1) to provide stable, biocontainment housing, husbandry and health care for mice (2) to provide a dedicated room for housing (Podl-124 of LRB) and on-site phenotyping procedures, (3) to assess the microbiological profile of each cohort and provides the Center Director with interpretation and advice regarding the results, and (4) to provide to the users ofthe phenotyping service, at the discretion ofthe Center Director, results and advice on the health status of submitted mice. The goal of the Animal Care Core is to support the operation of UMass MMPC with issues pertinent to animal care and quality of phenotyping mice.