Integration of Basic Neuroscience Research into Addiction Treatment Development

描述（由申请人提供）：本申请建议在马里兰州大学开展转化研究、博士前机构培训项目，该项目涉及物质使用的基本过程研究、预防和临床干预。该培训计划由马里兰州大学帕克分校（UMD）的多元化教师基础提供支持，并由巴尔的摩的马里兰州医学院，约翰霍普金斯大学和美国国立精神卫生研究院的教师补充。在拟议的培训计划的博士前学员将参加两年，一个与基础研究的重点，一个与临床成瘾治疗的重点。基础研究培训的核心组成部分将通过神经科学和认知科学（NACS）博士课程（www.nacs.umd.edu）提供，并将包括神经科学以及发展，社会和认知心理学的研究，使用生物，行为和神经行为方法来检查人类和非人类动物的相关过程。培训的临床核心组成部分将包括整个生命周期中物质使用的行为和药理学预防和治疗，以及研究物质相关问题的机会，包括艾滋病毒感染和心理并发症。所有培训学院都在进行关于药物使用和相关问题的应用研究（表2，研究兴趣）。该计划还包括几个完善的战略，以提高多样性。 公共卫生相关性：拟议的转化研究培训计划结合了基础过程研究，预防和临床干预，目标是培训博士前学生将神经科学，发展，社会和认知心理学应用于药物使用的新型治疗方法的开发。有几个完善的战略，以加强多样性，这是及时的，因为参与药物使用研究和治疗的少数民族精神病学家的代表性仍然不足。

DESCRIPTION (provided by applicant): This application proposes the development of a translational research, pre-doctoral institutional Training Program at the University of Maryland at the intersection of basic process research, prevention and clinical intervention for substance use. The Training Program is supported by a diverse base of faculty at the University of Maryland, College Park (UMD) and is supplemented with faculty from the University of Maryland Medical School in Baltimore, Johns Hopkins University, and the National Institutes of Mental Health. Predoctoral trainees in the proposed training program will participate for two years, one with a basic research focus and one with a clinical addictions treatment focus. The Basic Research Core components of training will be provided through the Neuroscience and Cognitive Science (NACS) doctoral Program (www.nacs.umd.edu) and will include study in neuroscience, as well as developmental, social, and cognitive psychology, using biological, behavioral and neurobehavioral methods to examine relevant processes in human and nonhuman animals. The Clinical Core components of training will include behavioral and pharmacological prevention and treatment of substance use across the lifespan as well as opportunities to study substance-related problems including HIV infection and psychological comorbidity. All training faculty are conducting research with application to substance use and related problems (Table 2, research interests). The Program also includes several well-developed strategies for enhancing diversity. PUBLIC HEALTH RELEVANCE: The proposed translational research Training Program combines basic process research, prevention and clinical intervention, with the goal of training predoctoral students to apply neuroscience, developmental, social, and cognitive psychology to the development of novel treatments for substance use. There are several well-developed strategies for enhancing diversity, which is timely given the continued under- representation of minority nsvcholoaists involved in substance use research and treatment.