Innovations in Pediatric Pain Research

本次申请以患者为中心的职业生涯中期研究人员奖的具体目标是1) 使用创新技术来改进对功能结果的测量并提供心理学 对患有慢性疼痛的青少年进行干预，以及2)为候选人提供受保护的时间和资源 有必要指导从事临床研究的博士后研究员和初级教员 在儿科疼痛中。候选人的方案研究侧重于开发创新方法，以 评估和治疗慢性疼痛、残疾和睡眠问题。在这个奖项的过程中，候选人 将使用创新技术完成研究，以改善疼痛和睡眠的测量 睡眠-觉醒行为的新的纵向研究。她将开发新的研究来检验这种药物的疗效 网络家庭认知行为干预对改善青少年精神障碍患者功能结局的研究 慢性疼痛。应聘者在为研究生提供指导方面有既定的记录， 心理学和医学方面的博士后研究员和初级教员。由此分配的增加的时间 获奖将使候选人有机会专注于培训更多的博士后研究员和教师。 该研究计划包括两个项目：美国国立卫生研究院/美国国立卫生研究院与美国国立卫生研究院合作的《青少年睡眠-觉醒障碍》。 慢性疼痛，以及一项新的互联网心理治疗慢性疼痛的临床试验 基于网络的CBT对患有慢性疼痛的青少年的客观功能结局的影响。 初级临床研究人员由候选人正在进行的研究的监督参与组成； 进行独立研究；有专业活动的经验，并实现专业 里程碑。通过人类调查计划，学员可以获得正式的教学计划，网址为： 俄勒冈健康与科学大学(OHSU)，NIH K30项目，有关于研究设计的研讨会， 随机对照试验、伦理学/人类受试者、拨款撰写和高级分析方法。 OHSU为这一奖项提供了一个理想的环境，因为建立了合作关系，承诺 以患者为导向的研究，以及强大的临床翻译研究中心的存在。 相关性(请参阅说明)： 候选人研究计划的公共卫生目标是为年轻人开发创新的治疗方法 有慢性疼痛和睡眠问题，可以提高目前的护理标准，最大限度地减少长期 有疼痛和残疾的问题。此外，候选人寻求培养下一代 这一领域以患者为中心的研究人员。

Ttie Specific Aims of this application for a Midcareer Investigator Award in Patient-Oriented Research are 1) to use innovative technologies to Improve measurement of functional outcomes and to deliver psychological interventions to youth with chronic pain, and 2) to provide the candidate protected time and resources necessary to mentor postdoctoral fellows and junior faculty members who are pursuing clinical Investigation in pediatric pain. The candidate's programmatic research has focused on developing innovative methods to assess and treat chronic pain, disability, and sleep problems. During the course of this award, the candidate will complete research studies using innovative technologies to improve measurement of pain and sleep in a novel longitudinal study of sleep-wake behaviors. She will develop new research to examine the efficacy of an internet family cognitive-behavioral intervention on improving functional outcomes in adolescents with chronic pain. The candidate has an established track record of providing mentorship to graduate students, postdoctoral fellows, and junior faculty in psychology and medicine. The increased time allotted by this award will give the candidate the opportunity to focus on training additional postdoctoral fellows and faculty. The Research Plan includes two projects: an NIH/NICHD ROl "Sleep-wake disturbances in adolescents with chronic pain," and a new clinical trial of an internet delivered psychological treatment for chronic pain "Effect of Web-based CBT on Objective Functional Outcomes in Youth with Chronic Pain." The Mentoring Plan for beginning clinical Investigators consists of supervised participation in the candidate's ongoing research; conduct of independent research; and experience in professional activities and achieving professional milestones. A formal didactic program is available to mentees through the Human Investigations Program at Oregon Health & Science University (OHSU), a NIH K30 program, with seminars on study design, randomized controlled trials, ethics/human subjects, grant writing, and advanced analytic approaches. OHSU provides an ideal setting for this award because of the established collaborations, commitment to patient-oriented research, and the presence of a strong Clinical Translational Research Center. RELEVANCE (See instructions): The public health goals of the candidate's research program are to develop innovative treatments for youth with chronic pain and sleep problems that can improve the current standard of care and minimize long-term problems with pain and disability. In addition, the candidate seeks to train the next generation of patient-oriented researchers in this area.