Anesthesiology & Perioperative Medicine Research Training

描述(由申请人提供)：本次竞争性续签申请(5T32GM086270)旨在为我们在华盛顿大学成功开展的麻醉学和围手术期医学研究培训的T32博士后培训计划的第6-10年提供资金。我们的主要目标是提供与麻醉学和围手术期医学相关的生物医学前沿(和新兴)领域的博士后水平的深入研究培训。我们第一个资助周期的学员在这个项目中取得了成功，他们发表了大量同行评议的出版物，获得了研究荣誉和奖项，获得了种子和启动资金，并在科学会议上发表了演讲。反映了我们系教员独特的跨学科构成和我们的教育使命，我们培训计划的一个重要扩展是为医学博士和临床博士-科学家提供跨专业教育。我们建议每年培训6名研究员，他们将在麻醉学和疼痛医学系的各种实验室之一或在基础科学和临床部门(例如，药理学、遗传学、儿科学、精神病学、生物伦理学)的合作研究中花费2-3年的累积时间。研究机会由60名NIH资助的教师导师提供，这些导师在博士后培训方面有成功的记录，包括从基于实验室的科学到翻译、临床和卫生服务研究的各种研究项目。核心教师研究负责人将帮助学员在与麻醉学和围手术期医学相关的六个主要研究领域(按字母顺序)与导师配对：1)心血管-肺部生物学，2)临床结果研究和流行病学，3)基因组科学和生物信息学，4)神经科学，5)疼痛，6)药理学。该计划的目标是：从国家申请者库中招募优秀的多样化博士后学员；为学员提供与其研究领域相关的跨学科理论和方法；为学员提供设计和实施麻醉学和围手术期医学高质量研究的实用技能(包括基础研究技能、了解负责任的研究行为、传播研究成果的能力，并获得成功的赠款技能和独立资助)；以及通过强有力的指导、广泛的研究机会和跨部门合作来创造一个支持性环境。受训人员的进展由一个专门针对同事的个别审查委员会定期监测，并向负责接收/雇用研究员并跟踪他们的进展情况的部门培训补助金咨询委员会报告摘要结果。此外，一个外部科学监督委员会每年开会，就培训计划的所有方面向计划主任提供建议。该计划的总体目的是培养麻醉学和围手术期医学研究的下一代临床科学家领导者。

DESCRIPTION (provided by applicant): This competitive renewal application (5T32GM086270) seeks funding for years 6-10 of our successful T32 postdoctoral training program in anesthesiology and perioperative medicine research training at the University of Washington. Our primary objective is to provide in-depth research training at the postdoctoral level in cutting edge (and emerging) areas of biomedical science related to anesthesiology and perioperative medicine. Trainees from our first funding cycle have demonstrated success in this program, producing numerous peer- reviewed publications, achieving research honors and awards, attaining seed and startup grant funding, and presenting at scientific conferences. Reflecting the unique interdisciplinary composition of our department faculty and our educational mission, an important expansion of our training program is to provide interprofessional education to M.D. and Ph.D. clinician-scientists. We propose training six fellows per year who will spend 2-3 years cumulative time in research in one of a variety of laboratories in the Department of Anesthesiology and Pain Medicine or in collaborating basic science and clinical departments (e.g., Pharmacology, Genetics, Pediatrics, Psychiatry, Bioethics). Research opportunities are offered by 60NIH- funded faculty mentors with proven records of success in the training of postdoctoral fellows, with diverse research programs ranging from laboratory-based science to translational, clinical, and health services research. Core faculty research leaders will help match trainees to mentors within six major research areas relevant to anesthesiology and perioperative medicine including (alphabetically): 1) cardiovascular-pulmonary biology, 2) clinical outcomes research & epidemiology, 3) genome sciences & bioinformatics, 4) neurosciences, 5) pain, and 6) pharmacology. Aims of the program are: to recruit outstanding diverse postdoctoral trainees from a national applicant pool; provide trainees with interdisciplinary theories and methods pertinent to their research area; provide trainees with the practical skills to design and conduct high quality research in anesthesiology and perioperative medicine (including fundamental research skills, understanding responsible conduct of research, ability to disseminate research findings, and acquire successful grantsmanship skills and independent funding); and to create a supportive environment through strong mentorship, a breadth of research opportunities, and collaboration across departments. Trainee progress is monitored regularly by an individualized fellow-specific review committee with summary findings reported to the departmental training grant advisory committee responsible for accepting/hiring fellows and following their progress. In addition, an external scientific oversight board meets yearly to offer advice to the program directors on all aspects of the training program. The overall intent of the program is to develop the next generation of clinician scientist leaders in anesthesiology and perioperative medicine research.