Anesthesiology & Perioperative Medicine Research Training

描述（由申请人提供）：此竞争性更新申请（5T32GM086270）为我们在华盛顿大学成功的T32麻醉学和围手术期医学研究培训博士后培训项目寻求6-10年的资助。我们的主要目标是在与麻醉学和围手术期医学相关的生物医学前沿（和新兴）领域提供深入的博士后研究培训。我们第一个资助周期的学员在这个项目中取得了成功，发表了许多同行评审的出版物，获得了研究荣誉和奖项，获得了种子和启动资助，并在科学会议上发表了演讲。我们的培训计划的一个重要扩展是为医学博士和博士提供跨专业教育，这反映了我们系教师独特的跨学科组成和我们的教育使命。我们建议每年培养6名研究员，他们将在麻醉学和疼痛医学系的不同实验室之一或在基础科学和临床合作部门（如药理学，遗传学，儿科学，精神病学，生物伦理学）进行2-3年的累计研究时间。研究机会由60名nih资助的教师导师提供，这些导师在培养博士后研究员方面有成功的记录，研究项目从实验室科学到转化、临床和卫生服务研究。核心教师研究领导将帮助学员与六个与麻醉和围手术期医学相关的主要研究领域的导师匹配，包括（按字母顺序排列）：1)心血管-肺生物学，2)临床结果研究与流行病学，3)基因组科学与生物信息学，4)神经科学，5)疼痛和6)药理学。项目目标：在全国范围内招收优秀、多元化的博士后培养人才；为学员提供与其研究领域相关的跨学科理论和方法；为学员提供设计和开展高质量麻醉学和围手术期医学研究的实用技能（包括基本研究技能，理解负责任的研究行为，传播研究成果的能力，以及获得成功的资助技能和独立资助）；通过强有力的指导、广泛的研究机会和跨部门的合作，创造一个支持性的环境。由个别评审委员会定期监察受训者的进度，并向负责接纳/聘用受训者及跟进其进度的部门培训补助金谘询委员会报告总结结果。此外，一个外部科学监督委员会每年召开一次会议，就培训计划的各个方面向项目主管提供建议。该计划的总体目的是培养下一代麻醉和围手术期医学研究的临床科学家领导者。

DESCRIPTION (provided by applicant): This competitive renewal application (5T32GM086270) seeks funding for years 6-10 of our successful T32 postdoctoral training program in anesthesiology and perioperative medicine research training at the University of Washington. Our primary objective is to provide in-depth research training at the postdoctoral level in cutting edge (and emerging) areas of biomedical science related to anesthesiology and perioperative medicine. Trainees from our first funding cycle have demonstrated success in this program, producing numerous peer- reviewed publications, achieving research honors and awards, attaining seed and startup grant funding, and presenting at scientific conferences. Reflecting the unique interdisciplinary composition of our department faculty and our educational mission, an important expansion of our training program is to provide interprofessional education to M.D. and Ph.D. clinician-scientists. We propose training six fellows per year who will spend 2-3 years cumulative time in research in one of a variety of laboratories in the Department of Anesthesiology and Pain Medicine or in collaborating basic science and clinical departments (e.g., Pharmacology, Genetics, Pediatrics, Psychiatry, Bioethics). Research opportunities are offered by 60NIH- funded faculty mentors with proven records of success in the training of postdoctoral fellows, with diverse research programs ranging from laboratory-based science to translational, clinical, and health services research. Core faculty research leaders will help match trainees to mentors within six major research areas relevant to anesthesiology and perioperative medicine including (alphabetically): 1) cardiovascular-pulmonary biology, 2) clinical outcomes research & epidemiology, 3) genome sciences & bioinformatics, 4) neurosciences, 5) pain, and 6) pharmacology. Aims of the program are: to recruit outstanding diverse postdoctoral trainees from a national applicant pool; provide trainees with interdisciplinary theories and methods pertinent to their research area; provide trainees with the practical skills to design and conduct high quality research in anesthesiology and perioperative medicine (including fundamental research skills, understanding responsible conduct of research, ability to disseminate research findings, and acquire successful grantsmanship skills and independent funding); and to create a supportive environment through strong mentorship, a breadth of research opportunities, and collaboration across departments. Trainee progress is monitored regularly by an individualized fellow-specific review committee with summary findings reported to the departmental training grant advisory committee responsible for accepting/hiring fellows and following their progress. In addition, an external scientific oversight board meets yearly to offer advice to the program directors on all aspects of the training program. The overall intent of the program is to develop the next generation of clinician scientist leaders in anesthesiology and perioperative medicine research.