BIOSTATISTICS AND DATA MANAGEMENT CORE

该计划项目将生成来自各种来源的大量数据。会是 对项目的成功至关重要的是以一致的方式处理这些数据并使用 适当的统计方法。生物统计和数据管理核心(BDC)将填补这一角色，提供 为所有三个研究项目提供全面的数据相关支持。将由提供的支持类型 数据中心将包括：为新的数据收集设计表格和调查表；处理其他两个核心产生的新数据；数据检查，包括检查逻辑不一致和潜在的异常值；创建结合表型、遗传和暴露数据的数据库；协助制定假设；分析数据，包括测试和估计空气污染和遗传影响；编写手稿以供出版； 维护可由所有调查人员访问以进行文件共享的中央计算资源 运行软件程序。

This Program Project will generate a very large amount of data coming from a variety of sources. It will be essential to the success of the project that these data be handled in a consistent manner and analyzed using appropriate statistical methods. The Biostatistics and Data Management Core (BDC) will fill this role, providing comprehensive data-related support to all three research projects. The types of support that will be provided by the BDC will include: designing forms and questionnaires for new data collection; processing incoming data generated by the other two Cores; data checking, including checks for logical inconsistencies and potential outliers; creating databases that combine phenotypic, genetic and exposure data; assisting in the development of hypotheses; analyzing data, including testing and estimating air pollution and genetic effects; preparing manuscripts for publication; maintaining a central computing resource that may be accessed by all investigators for file sharing and running software programs.