Center for Drug Abuse Prevention in the Child Welfare System

说明（由申请人提供）：本申请书为儿童福利系统P30预防药物滥用中心申请。该中心将继续支持最初通过NIDA P20机制创建的基础设施，以系统地整合和扩展针对CWS科学、实践和政策的工作。该中心旨在实现以下目标：(a)进一步明确概念模型，为与CWS儿童和家庭相关的干预措施的发展提供信息；(b)在常规CWS实践中增加基于证据的干预措施的实施，最终目标是(c)减少CWS人群中药物滥用和相关问题的发生率。该中心由两个核心组成。行政核心将提供共享资源、领导和监督，以整合和扩展我们目前、以前和计划中的CWS研究的知识；促进与CWS研究人员的合作，向学术界和社会政策界传播主要研究成果；支持7-10项试点研究；促进早期职业科学家的专业发展。能力增强核心将提供基础设施，通过以下三个方面的活动，将与预防慢性疾病药物滥用有关的新的关键领域纳入我们当前和未来的研究：计算基于证据的干预措施在CWS安置结果中的成本和直接收益，提高我们实施药物滥用预防干预的能力，这些干预措施包括生物社会措施和压力神经生物学和遗传学方法，并促进我们对父亲，药物滥用和CWS家庭中儿童结局的作用的理解。拟议的工作包括11名多学科科学家（包括5名早期职业研究者），并将利用我们32个联邦资助项目的基础。这两个核心将协同工作，并为当前和未来的项目提供共享资源，为旨在预防慢性精神病患者家庭滥用药物的具体干预措施提供信息。

DESCRIPTION (provided by applicant): This application is for a P30 Center for Drug Abuse Prevention in the Child Welfare System (CDAP-CWS). The Center would continue support for an infrastructure that was originally created through a NIDA P20 mechanism for the systematic integration and extension of work aimed at CWS science, practice, and policy. The proposed Center aims to accomplish the following: (a) further specify conceptual models to inform the development of interventions relevant to CWS children and families, (b) increase the implementation of evidence-based interventions into routine CWS practice, with the ultimate goal of (c) reducing the incidence of drug abuse and related problems in CWS populations. Two cores will comprise the Center. The Administrative Core will provide shared resources, leadership, and oversight to integrate and extend knowledge from our current, previous, and planned CWS studies; facilitate collaborations with CWS researchers to disseminate key findings to academic and social policy communities; support 7-10 pilot studies; and facilitate the professional development of early career scientists. The Capacity Enhancement Core will provide the infrastructure to incorporate new key areas related to CWS drug abuse prevention into our current and future studies through activities in three areas: calculating the costs and immediate benefits of evidence-based interventions in the CWS on placement outcomes, improving our ability to implement drug abuse preventive interventions that are informed by or incorporate biosocial measures and methods of stress neurobiology and genetics, and facilitating our understanding of the role of fathers, drug abuse, and child outcomes in CWS families. The proposed work includes 11 multidisciplinary scientists (including 5 early career investigators) and will utilize our base of 32 federally funded projects. The two cores will work synergistically and provide shared resources among current and future projects to inform specific interventions aimed at preventing drug abuse in CWS families.