FACTORS UNDERLYING ALOPECIA IN RHESUS MACAQUES

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 脱发，或脱发，是研究机构中非人类灵长类和其他动物的常见问题。脱发被认为是健康受损的潜在指标，但令人惊讶的是，很少有研究调查这种疾病的潜在病因和治疗方法。这项研究调查了一些可能与雌性猴子脱发相关的潜在行为因素。我们评估了16只成年雌性恒河猴的脱发和行为，这些成年雌性恒河猴生活在两个独立的环境控制的户外庇护所之一。为了评估脱发，我们在每只猴子的年度体检中拍摄了它们的照片。我们还获得了一份头发样本，将用于皮质醇含量的检测。我们还通过对动物进行重点观察来评估行为。我们发现脱发模式与拔头发行为有关。只有患有斑片状脱发的动物才会进行拔毛行为(通常是作为接受者)。患有这三种脱发模式的动物在美容或其他行为上没有差异。这一发现表明，自拔毛发等行为可能与特定的表型模式有关。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Hair loss, or alopecia, is a common problem among nonhuman primates and other animals in research facilities. Alopecia is recognized as a potential indicator of compromised well being, yet there are surprisingly few studies investigating potential etiologies and treatments for this condition. This study examined some potential behavioral factors that may correlate with alopecia in female monkeys. We assessed both alopecia and behavior in 16 adult female rhesus macaques living in one of two separate outdoor environmentally controlled shelter houses. To assess alopecia, we took photos of each of the monkeys during their annual physical exams. We also obtained a hair sample, which will be assayed for cortisol content. We also assessed behavior by taking focal observations on the animals. We found that alopecia pattern was associated with hair pulling behavior. Only animals with a patchy pattern of alopecia engaged in hair pulling behavior (typically as the recipient). There were no differences in grooming or other behaviors among animals with the three patterns of alopecia. This finding suggests that self-epilating behaviors such as hair pulling may be associated with specific phenotypic patterns.