GABA-A RECEPTOR SUBTYPE MECHANISMS IN THE ABUSE-RELATED EFFECTS OF ALCOHOL

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 酒精中毒是一个公共卫生问题，与衰弱的医疗，社会和心理后果有关。 本项目研究了特定的GABA能受体机制，这些机制是酒精的主观、强化和复发诱导作用的基础，结果将有助于确定酒精滥用和复发的药理学管理的受体靶点。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Alcoholism is a public health problem that is associated with debilitating medical, social, and psychological consequences. This project investigates specific GABAergic receptor mechanisms underlying the subjective, reinforcing, and relapse-inducing effects of alcohol and results will aid identification of receptor targets for the pharmacological management of alcohol abuse and relapse.