China Health and Retirement Longitudinal Study

描述(申请人提供)：本申请请求支持中国健康与退休纵向研究(CHARLS)于2011年秋季收集的静脉血生物标记物样本的分析。这是对现有R01拨款的竞争性修订，将支持CHARLS小组的前两次国家浪潮的收集，第一次是 2011年部署，2013年部署第二架。中国健康与退休纵向研究是由北京大学国家发展研究院(中国经济研究中心)与卫生部中国疾病预防控制中心共同开展的一项针对中国老年人的调查。它是基于成员年龄在45岁及以上的家庭的样本。它旨在产生一个高质量的公共微观数据库，可以提供从社会经济状况到健康状况的广泛信息，服务于中国老年人科学研究的需求。CALLS的设计还允许与健康和退休研究(HRS)系列研究中的其他研究进行比较。在本申请所要求的支持下，我们将分析在国家研究第一波中从大约17,600人中收集的静脉血，以确定炎症水平、糖化血红蛋白、血糖、血脂和肾功能的指标。这将使我们能够将这些生物标志物的水平与中国体内的社会经济、行为和背景变量进行比较，并与其他国际调查的其他变量的水平和联系进行比较。 公共卫生相关性：中国健康与退休纵向研究(CHARLS)将丰富老龄化研究的国际格局。CALLS密切跟踪世界各地现有的健康与退休研究的形式和内容，以便为学者提供从事比较研究以及对中国特殊情况的研究的能力。CHARLS的前两次全国性浪潮计划在2011年和2013年进行。这一竞争性修订将使CHARLS能够增加在第一波数据收集期间收集的静脉血液样本中重要生物标记物的结果。

DESCRIPTION (provided by applicant): This application requests support for the assay of venous blood biomarker samples now collected in the fall of 2011 in the China Health and Retirement Longitudinal Study (CHARLS). This is a competing revision to an existing R01 grant that will support the collection of the first two national waves of the CHARLS panel, the first was fielded in 2011 and the second in 2013. The China Health and Retirement Longitudinal Study (CHARLS) is a survey of the elderly in China, run by the National School for Development (China Center for Economic Research) at Peking University, together with the Chinese Center for Disease Control and Prevention (CDC) in the Ministry of Health. It is based on a sample of households with members aged 45 years and older... It is designed to produce a high quality public micro-database, which can provide a wide range of information from socio-economic status to health conditions, to serve the needs of scientific research on the elderly in China. CHARLS is also designed to allow comparisons with other studies in the Health and Retirement Study (HRS) family of studies. With the support requested in this application we will assay venous blood collected in wave 1 of the national study from approximately 17,600 people for indicators of the level of inflammation, glycosylated hemoglobin, plasma glucose, lipids, and kidney functioning This will allow the comparison of levels of these biomarkers with socioeconomic, behavioral and contextual variables within China, with the comparison of levels and links with other variables other international surveys. PUBLIC HEALTH RELEVANCE: The China Health and Retirement Longitudinal Study (CHARLS) will enrich the international landscape of aging studies. CHARLS follows closely the format and content of existing Health and Retirement Studies around the world in order to provide the capability for scholars to engage in comparative studies as well as studies of the special conditions in China. The first two national waves of CHARLS are scheduled for 2011 and 2013. This competitive revision will enable CHARLS to add results on important biomarkers from venous blood samples collected during the first wave of data collection.