TESTING AND INVESTIGATION OF M2M IMAGING COIL

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 目标： --测试和评估用于鼠标成像的双调M2M 129Xe-1H线圈的性能。这将包括热129Xe体模的详细成像和光谱分析，并将继续进行小鼠体内成像。 --为小鼠的2D和3D 129Xe通风成像建立可达到的分辨率。 活体显微镜中心购买了第一个用于2T磁体的129Xe-1H双调谐小鼠成像线圈。这个项目的目的是测试这个线圈，并在小鼠身上建立129Xe磁共振成像的基线性能指标。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. AIMS: -- To test and evaluate the performance of the dual-tuned M2M 129Xe-1H coil for mouse imaging. This will include detailed imaging and spectroscopy of a thermal 129Xe phantom and will follow on with in vivo mouse imaging. -- Establish achievable resolution for 2D and 3D 129Xe ventilation imaging in the mouse. The Center of In Vivo Microscopy purchased the first of its kind 129Xe-1H dual-tuned mouse imaging coil for the 2T magnet. The purpose of this project is to put this coil through its paces and establish baseline performance metrics for 129Xe MRI in the mouse.