METAPHASE SPINDLE PROTEOME

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 我们的目标是了解细胞质分裂的机制。我们正在使用蛋白质组学和比较基因组学技术来确定特定细胞周期阶段所需的蛋白质。通过分析不同细胞周期阶段的蛋白质组成，可以通过精确定位特定细胞周期阶段的蛋白质来更好地理解细胞分裂的机制。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Our goal is to understand the mechanisms of cytokinesis. We are using proteomic and comparative genomic techniques to identify proteins that are required during specific cell cycle stages. Analyzing protein composition of different cell stages may lead to better understanding of the mechanism of cell division by pinpointing proteins specific to particular cell cycle stage.