Visual Impairment, Treatment and Effects on the Elderly
Visual Impairment, Treatment and Effects on the Elderly
批准号:
8316266
负责人:
FRANK A SLOAN
金额:
$30.59万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-09-30 至 2016-08-31
关键词:
AccountingAddressAdherenceAdmission activityAffectAge related macular degenerationArgonBlindnessCardiovascular systemCaringCessation of lifeClinicalCognitiveComplementComplicationComplications of Diabetes MellitusDataDatabasesDiabetes MellitusDiabetic RetinopathyDiagnosisDiagnosticDiagnostic ProcedureDiffusionDrug PrescriptionsEffectivenessElderlyEnd stage renal failureExpert OpinionEyeEye diseasesGuidelinesHealthHealth ServicesHeart DiseasesHip FracturesIndividualInjection of therapeutic agentInterventionKidney DiseasesLaser SurgeryLasersLight CoagulationLongevityLow-Level Laser TherapyMacular degenerationMedicareMedicare claimMental DepressionMethodsMonitorMoralsNeuropathyNursing HomesOlder PopulationOperative Surgical ProceduresOutcomePatternPersonal Health ServicesPersonal SatisfactionPersonsPharmaceutical PreparationsPharmacotherapyPhotochemotherapyPhysiciansPractice GuidelinesProcessProductionProductivityRandomized Controlled TrialsRecommendationResearchRetinal DetachmentRetirementRiskRoleRunningSamplingServicesSeveritiesSocial WelfareSpecialistSteroidsStrokeSurveysTechnologyTestingTherapeuticTherapeutic InterventionTherapeutic procedureTimeVisionVisitVisualVisual impairmentVital StatisticsVitrectomyVitreous HemorrhageWorkage relatedbasebeneficiarybevacizumabcerebrovascularcomparative effectivenesscostcost effectivenessdiabeticdiet and exercisediscountingeffective therapyfallshazardimprovedinnovationintravitreal injectionlaser photocoagulationmacular edemanew technologypreferenceproliferative diabetic retinopathytreatment effect
中文摘要
工作总结
这项为期3年的研究有3个具体目标:(1)检查眼睛护理诊断和诊断的纵向使用模式
主要眼科疾病的治疗服务;(2)评估新技术是否减少了视力损失
老年性黄斑变性(AMD)眼科治疗的创新和更高的治疗强度
糖尿病眼病(包括全身和眼部疾病);和(3)评估利用率,遵守指南,以及
心血管、脑血管和肾病结果。AIM 1将双曲贴现作为一种
解释治疗AMD的新疗法的不使用和推广。AIM 2进行比较
老年性黄斑变性与糖尿病眼部治疗对视力及其他影响的疗效分析
并发症。目标3调查诊断和治疗程序的效果,包括处方药,
使用工具变量(IV)和对照对心脑血管和肾病预后的影响
函数方法。为了补充IV分析,本研究调查了选择护理的过程,
评估临床、人口学和财务因素等观察指标在选择中的作用。全国性的,
将使用的纵向数据库包括:与生命统计信息合并的Medicare 5%索赔数据
1991-2010年;医疗保险受益人的健康和退休调查数据与医疗保险索赔合并
1993-2008年;Medicare当前受益人调查数据也与来自
医疗保险,1991-2009年。
英文摘要
Summary of work
This 3-year study has 3 specific aims: (1) Examine patterns of longitudinal use of eye care diagnostic and
therapeutic services for major eye diseases; (2) Assess whether visual loss has been reduced by new
innovations in ocular therapy for age-related macular degeneration (AMD) and greater intensity of therapy in
diabetic eye diseases (both systemic and ocular); and (3) Assess utilization, conformance with guidelines, and
cardiovascular, cerebrovascular, and nephropathy outcomes. Aim 1 investigates hyperbolic discounting as an
explanation of nonuse and diffusion of new therapies for treatment of AMD. Aim 2 performs comparative
effectiveness analysis of effects of AMD therapies and diabetic eye therapies on visual and other
complications. Aim 3 investigates effects of diagnostic and therapeutic procedures, including prescribed drugs,
on cardiovascular, cerebrovascular, and nephropathy outcomes using instrumental variable (IV) and control
function methods. To complement the IV analysis, this study investigates the process of selection into care,
assessing roles of such observables as clinical, demographic and financial factors on selection. National,
longitudinal data bases to be used include: Medicare 5% claims data merged with vital statistics information
from 1991-2010; Health and Retirement Survey data on Medicare beneficiaries merged with Medicare claims
for 1993-2008; and Medicare Current Beneficiary Survey data also merged with administrative information from
Medicare, 1991-2009.
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DOI:
10.1097/iae.0b013e3182831248
发表时间:
2013-05
期刊:
Retina (Philadelphia, Pa.)
影响因子:
--
作者:
[Hahn P, Acquah K, Cousins SW, Lee PP, Sloan FA]
通讯作者:
Sloan FA
DOI:
10.1016/j.jdiacomp.2015.07.005
发表时间:
2015-11
期刊:
Journal of diabetes and its complications
影响因子:
3
作者:
[Chen Y, Sloan FA, Yashkin AP]
通讯作者:
Yashkin AP
Longitudinal incidence of adverse outcomes of age-related macular degeneration.
年龄相关性黄斑变性不良后果的纵向发生率。
DOI:
10.1001/archophthalmol.2008.613
发表时间:
2009
期刊:
Archives of ophthalmology (Chicago, Ill. : 1960)
影响因子:
--
作者:
[Wysong,Ashley, Lee,PaulP, Sloan,FrankA]
通讯作者:
Sloan,FrankA
Effects of receipt of guideline-recommended care on onset of diabetic retinopathy and its progression.
接受指南推荐的护理对糖尿病视网膜病变发病及其进展的影响。
DOI:
10.1016/j.ophtha.2009.03.010
发表时间:
2009
期刊:
Ophthalmology
影响因子:
13.7
作者:
[Sloan,FrankA, Grossman,DanielS, Lee,PaulP]
通讯作者:
Lee,PaulP
DOI:
10.14423/smj.0000000000000214
发表时间:
2015-01
期刊:
Southern medical journal
影响因子:
1.1
作者:
[Gray N, Picone G, Sloan F, Yashkin A]
通讯作者:
Yashkin A
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