Training in Translational Tobacco Science

描述（由申请人提供）：此K 05赠款将提供培训，教育和研究经验，使博士蒂莫西·贝克进行开创性的研究，跨学科和翻译，对烟草使用和其他成瘾性疾病。具体而言，该研究将促进来自不同学科和许多合作者的理论，数据和方法的整合。此外，它将允许他进行转化研究，其中创新的基础科学模型和方法用于产生新的治疗和评估;即促进基础科学发现和观点的转移，使其实现更有效的现实应用。请求的支持也将促进贝克博士对未来成瘾科学家骨干的教学和培训，特别是在提供临床科学培训方面，强调具有明显应用潜力的跨学科研究战略。为了实现这些目标，申请人将：（1）利用所要求的支助减少其行政和教学义务;（2）上课，进行密集的阅读和研究，并向与申请人的研究特别相关的目标领域的专家咨询;（三）设计和开展新的研究，为解决烟草使用问题的跨学科和转化研究提供绝佳机会，其他成瘾性疾病;（4）培养新的烟草科学家。对新科学家的培训将通过对研究生和博士后学生的辅导活动、额外的教学指导以及为国家招聘的初级科学家提供的强化讲习班来完成。拟议的工作将受益于申请人的研究环境中提供的巨大资源，以及他与一个大型跨学科团队正在进行的研究。这项K 05补助金应该通过提高贝克博士、他的合作者和他训练的人对成瘾性疾病的研究质量来造福公共卫生。具体而言，这种支持应促进更好地了解烟草使用和其他成瘾性疾病，并最终通过为这些毁灭性疾病提供更有效的治疗方法来影响国民的健康。

DESCRIPTION (provided by applicant): This K05 grant will provide training, educational, and research experiences that allow Dr. Timothy Baker to perform groundbreaking research, both transdisciplinary and translational, on tobacco use and other addictive disorders. Specifically, the research will foster the integration of theories, data, and methods from diverse disciplines and among many collaborators. In addition, it will permit him to conduct translational research in which innovative basic science models and methods are used to generate new treatments and assessments; viz. to facilitate the transfer of basic science findings and perspectives so that they achieve more effective real-world application. The requested support also will facilitate Dr. Baker's teaching and training of the future cadre of addiction scientists, especially in providing clinical science training that emphasizes transdisciplinary research strategies with clear potential for application. To accomplish these aims, the applicant will: (1) use the requested support to reduce his administrative and teaching obligations; (2) take classes, engage in intensive reading and study, and consult with experts in targeted areas of special relevance to the applicant's research; (3) design and conduct new research studies that provide outstanding opportunity for transdisciplinary and translational research addressing tobacco use and other addictive disorders; and, (4) train new tobacco scientists. This training of new scientists will be accomplished via mentoring activities with graduate and post-doctoral students, additional didactic instruction, and intensive workshops offered to junior scientists recruited nationally. The proposed work will benefit from the tremendous resources available in the applicant's research environment and by his on-going research with a large transdisciplinary team. This K05 grant should benefit public health by enhancing the quality of research on addictive disorders performed by Dr. Baker, his collaborators, and those he trains. Specifically, this support should promote better understanding of tobacco use and other addictive disorders and, ultimately, impact the health of the nation by producing more effective treatments for these devastating diseases.