Graduate Training in Cellular and Molecular Pathogenesis of Human Diseases

描述(由申请人提供)：细胞和分子病理学(CMP)研究生培训计划是由威斯康星大学麦迪逊研究生院、病理学系和医学与公共卫生学院(SMPH)联合举办的。该计划吸引了来自威斯康星州大学研究生院和医学院20个系的54名培训人员，横跨3个不同的学院(医学、兽医和文学与科学)。CMP的目标是为博士前培训创造一个激励和强大的跨学科知识环境，嵌入令人兴奋和具有挑战性的基础和临床翻译研究。CMP包括基础研究科学家和临床医生的积极参与，重点是了解人类重大疾病的发病机制，并发展将生物学知识转化为临床应用所需的技能。该项目有28名博士和26名医学博士或博士资助的教职员工。我们正在申请资金，用于培训2，3，4和5年级的1年级和4年级的2名博士前研究生。我们将根据提名CMP培训师的推荐、研究经验、推荐信和增强多样性的潜力来挑选高素质的候选人，并为我国与健康相关的研究需求做出重大贡献。学员将获得不超过3年的培训补助金支持。我们的课程提供现代病理生物学基本概念的跨学科和综合培训，重点是生化、细胞和分子方法，以及在理解疾病基本基础方面的严格深入研究培训。我们让我们的成员参加教学病理生物学课程和翻译临床活动。我们提供癌症病理生物学、神经系统和免疫系统疾病方面的深入研究培训。该课程还有助于培养学生的教学和领导能力。越来越多的公众要求加强对研究支出的问责，以及将基础科学进步转化为临床应用的需要，这要求将医学培训更多地纳入研究生教育。我们的学员将拥有病理生物学的基础知识和深入的研究经验，并结合对翻译临床研究的理解。 相关性：CMP研究生计划的主要目标是为我们的毕业生在科学研究和教育领域从事富有成效的职业生涯做好准备，并使他们能够为我国与健康相关的研究需求做出重大贡献。

DESCRIPTION (provided by applicant): The Cellular and Molecular Pathology (CMP) Graduate Training Program is a joint venture of the UW-Madison Graduate School, the Department of Pathology and the School of Medicine and Public Health (SMPH). The Program draws 54 trainers from 20 departments across the UW graduate campus and Medical School, spanning 3 separate colleges (Medicine, Veterinary Medicine and Letters & Science). The goal of the CMP is to create a stimulating and robust intellectual interdisciplinary environment for predoctoral training embedded in an exciting and challenging basic and clinical translational research. CMP includes the active participation of basic research scientists and clinicians with a focus on understanding the pathogenesis of major human diseases and developing skills needed to move biological knowledge toward clinical application. The program has 28 PhD and 26 MD or MD/PhD funded faculty. We are requesting funds for training 2 predoctoral students in Year 1 and 4 in Years 2,3,4 and 5. Highly qualified candidates will be selected based on the recommendation of nominating CMP trainer, research experiences, letters of recommendation and potential to enhance diversity and make significant contributions toward the health-related research needs of our nation. Trainees will be supported by the training grant for no longer than 3 years. Our curriculum provides interdisciplinary and integrated training in fundamental concepts in modern pathobiology with an emphasis on biochemical, cellular and molecular approaches and rigorous in-depth research training in understanding of the fundamental bases of diseases. We engage our members in didactic pathobiology courses and translational clinical activities. We provide in-depth research training in the pathobiology of cancer, nervous system and immune system diseases. CMP also helps students to develop teaching and leadership skills. Increasing public demand for greater accountability for research expenditures and the need for converting basic science advances into clinical applications call for higher integration of medical training into graduate education. Our trainees will have fundamental knowledge and in-depth research experience in pathobiology combined with understanding of translational clinical research. RELEVANCE: The primary objective of the CMP Graduate Program is to prepare our graduates for productive careers in scientific research and education and to position them to make significant contributions toward the health-related research needs of our nation.