Comprehensive Anesthesia Research Training

描述（由申请人提供）：我们的培训补助金目标是确保我们的学员学习最先进的研究技术，提出研究问题的基本原理，以及分析数据和报告结果所涉及的批判性思维。培训计划必须培训研究人员制定和编写赠款，设计和进行实验，进行适当的统计分析，并了解临床研究所涉及的法规。为了成为多才多艺的生物医学研究人员，我们将让参与以患者为导向的研究的学员了解相关的基础科学研究原理和相应的实验室技能。我们的目标是优化我们有才华的基础和医生科学家教师与学员之间的互动，以产生高质量的翻译研究人员，能够与临床研究人员和基础科学研究人员合作。我们将我们的教师组织成五个综合科学轨道：神经科学，重症监护，疼痛和 成瘾，血管生物学和生物工程，基因组学和流行病学。一个适当的高级研究员领导每一个这些轨道，每个轨道包括物理学家，科学家和基础科学家。该结构旨在促进富有成效的互动，并在具有共同兴趣的研究人员之间开发项目赠款，同时允许在麻醉和围手术期医学实践的不同领域进行培训。我们计划的使命之一是提供适用于动态临床环境的临床研究方法的结构化培训。最终目标是培养学员成为一名独立的研究者，他们将在临床和基础研究设计方法，分析技术方面得到良好的培训，并在学术研究环境中变得富有成效，并将利用这些技能为改善患者结局的发现做出贡献。该计划需要一个为期两年的承诺，是面向学员谁将完成临床麻醉培训。然而，我们也将考虑全职研究科学家在基础或临床领域的工作支持学术麻醉学的使命。因为我们已经实施了一个新的创新的四年居住计划，其中包括2年的保护研究时间，将有一个培训插槽（2/年）的需求增加，从今年18开始。因此，我们要求维持目前的拨款 在第16和17年，然后要求增加一个名额，总共四个名额，分别用于第18、19和20年。我们预计，第一年的创新研究轨道居民将加入T32将在他们的CA 4年18。 公共卫生相关性：医生和相关科学家越来越需要将基本的科学发现带给患者，并证明这些发现可以改善患者的预后。在患者中测试药物和器械以及开发生物标志物需要法规事务、临床试验设计和相关基础知识。 科学原理和技术的发现。该培训补助金将培训医生和相关科学家，使他们能够为患者带来更多的科学发现，并仔细记录这些发现的安全性，有效性和重要性。

DESCRIPTION (provided by applicant): Our training grant objectives are to ensure that our trainees learn state-of-the-art research techniques, the fundamentals of posing a research question, and the critical thinking involved with analyzing data and reporting their results. A training program must train researchers to formulate and write grants, to design and conduct experiments, to perform appropriate statistical analyses and to understand the regulations that are involved in clinical research. To become versatile biomedical researchers, we will have our trainees that are involved in patient-oriented research acquire an understanding of relevant basic science research principals and the corresponding laboratory skills. Our goal is to optimize the interactions between our talented basic- and physician-scientist faculty with trainees in order to produce high quality translational researchers that are capable of collaborating with both clinical researchers and with basic science researchers. We have organized our faculty into five integrated scientific tracks: Neuroscience, Critical Care, Pain and Addiction, Vascular Biology and Bioengineering, and Genomics and Epidemiology. An appropriate senior researcher leads each of these tracks and each track includes physician-scientists and basic scientists. This structure is proposed to foster productive interactions and develop program project grants amongst the researchers with common interests, while allowing training in the diverse areas important to the practice of anesthesia and perioperative medicine. One of the missions of our program is to provide structured training in clinical research methods that are applicable to the dynamic clinical environment. The ultimate goal is to prepare the trainee to become an independent investigator, who will be well trained in clinical and basic research study design methods, analytical techniques and become productive in an academic research environment, and will use the skills to contribute to discoveries that will improve patien outcomes. The program requires a two-year commitment and is geared towards trainees who will have completed training in clinical anesthesia. However, we will also consider full-time research scientists in either basic or clinical arenas whose work supports the mission of academic anesthesiology. Because we have implemented a new innovative four-year residency program that includes 2 years of protected research time, there will be an increased demand for training slots (2/yr) starting in year 18. Therefore, we request to maintain the current allocation in Years 16 and 17, and then request an additional slot, to a total of four, for years 18, 19 and 20. We anticipate that the 1st year innovative research track residents will join the T32 will be year 18 in their CA4 year. PUBLIC HEALTH RELEVANCE: There is an increased need for physicians and allied scientists to bring basic scientific discoveries to patients, and to prove that these discoveries improve patient outcomes. Testing medications and devices in patients and development of biomarkers requires knowledge in regulatory affairs, clinical trial design, and relevant underlying scientific principles and techniques involved in discovery. This training grant will train physicias and allied scientists so that they can bring more scientific discoveries to patients and carefully document the safety, efficacy, and importance of the discoveries.