Graduate Training in Cellular and Molecular Pathogenesis of Human Diseases

描述（由申请人提供）：细胞和分子病理学（CMP）研究生培训计划是威斯康星大学麦迪逊分校研究生院，病理学系和医学与公共卫生学院（SMPH）的合资企业。该计划吸引了来自UW研究生院和医学院20个部门的54名培训师，跨越3个独立的学院（医学，兽医学和文学与科学）。CMP的目标是创造一个刺激和强大的知识跨学科环境，用于嵌入令人兴奋和具有挑战性的基础和临床转化研究的博士前培训。CMP包括基础研究科学家和临床医生的积极参与，重点是了解主要人类疾病的发病机制，并培养将生物学知识推向临床应用所需的技能。该计划有28名博士和26名MD或MD/PhD资助的教师。我们正在申请资金，用于在第1年和第4年培训2名博士生。高素质的候选人将根据提名CMP培训师的建议，研究经验，推荐信和潜力来选择，以提高多样性，并对我们国家的健康相关的研究需求作出重大贡献。培训补助金将为受训人员提供不超过3年的支助。我们的课程提供现代病理生物学基本概念的跨学科和综合培训，重点是生物化学，细胞和分子方法以及对疾病基本基础的理解的严格深入研究培训。我们让我们的成员参与教学病理学课程和转化临床活动。我们在癌症，神经系统和免疫系统疾病的病理生物学方面提供深入的研究培训。CMP还帮助学生发展教学和领导技能。越来越多的公众要求对研究支出承担更大的责任，并需要将基础科学的进步转化为临床应用，这就要求将医学培训更好地融入研究生教育。我们的学员将拥有病理生物学的基础知识和深入的研究经验，并了解转化临床研究。 相关性：CMP研究生课程的主要目标是为我们的毕业生在科学研究和教育方面的富有成效的职业生涯做好准备，并使他们能够为我们国家的健康相关研究需求做出重大贡献。

DESCRIPTION (provided by applicant): The Cellular and Molecular Pathology (CMP) Graduate Training Program is a joint venture of the UW-Madison Graduate School, the Department of Pathology and the School of Medicine and Public Health (SMPH). The Program draws 54 trainers from 20 departments across the UW graduate campus and Medical School, spanning 3 separate colleges (Medicine, Veterinary Medicine and Letters & Science). The goal of the CMP is to create a stimulating and robust intellectual interdisciplinary environment for predoctoral training embedded in an exciting and challenging basic and clinical translational research. CMP includes the active participation of basic research scientists and clinicians with a focus on understanding the pathogenesis of major human diseases and developing skills needed to move biological knowledge toward clinical application. The program has 28 PhD and 26 MD or MD/PhD funded faculty. We are requesting funds for training 2 predoctoral students in Year 1 and 4 in Years 2,3,4 and 5. Highly qualified candidates will be selected based on the recommendation of nominating CMP trainer, research experiences, letters of recommendation and potential to enhance diversity and make significant contributions toward the health-related research needs of our nation. Trainees will be supported by the training grant for no longer than 3 years. Our curriculum provides interdisciplinary and integrated training in fundamental concepts in modern pathobiology with an emphasis on biochemical, cellular and molecular approaches and rigorous in-depth research training in understanding of the fundamental bases of diseases. We engage our members in didactic pathobiology courses and translational clinical activities. We provide in-depth research training in the pathobiology of cancer, nervous system and immune system diseases. CMP also helps students to develop teaching and leadership skills. Increasing public demand for greater accountability for research expenditures and the need for converting basic science advances into clinical applications call for higher integration of medical training into graduate education. Our trainees will have fundamental knowledge and in-depth research experience in pathobiology combined with understanding of translational clinical research. RELEVANCE: The primary objective of the CMP Graduate Program is to prepare our graduates for productive careers in scientific research and education and to position them to make significant contributions toward the health-related research needs of our nation.