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中文摘要
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这项赠款申请是为了请求对第41-45届国际麻醉品研究会议(INRC)的支持。第41次会议将于2010年7月11日至16日在瑞典马尔默举行,将是IUPHAR会议的卫星会议。第42届INRC将与CPDD联合举行会议,将在美国佛罗里达州好莱坞举行。目前正在计划最终确定第43至45届INRC的场馆。多年来,这些会议一直是传播和交流有关阿片类药物和内源性阿片系统生物医学研究信息的最负盛名的国际会议。这些主题涵盖了从分子机制到行为研究和临床发现。请求提供支助的主要是部分旅费,以使青年科学家,即研究生、博士后研究员和初级教员能够参加会议。被邀请的研讨会演讲者,通常不是INRC的参与者,将得到部分支持。申请用于行政和会议费用的资金约占申请资金总额的10%。今年会议的全体演讲者是:Tomas Hockfit教授(瑞典Inst卡罗林斯卡)、Tony Yaksh教授(美国加州大学旧金山分校)和Jorgen Engel教授(瑞典德堡大学)。十个研讨会将涵盖应用中描述的广泛主题,从新型阿片配体、阿片肽和受体的表观遗传学、神经病理性疼痛中的阿片类药物、酒精和赌博成瘾以及阿片类药物与大麻的相互作用。在每一次研讨会上,初级研究人员将选择一些相关的投稿论文进行口头陈述。将有两个海报会议,在那里总是有很多交流和讨论。还计划为年轻科学家举办一次数据闪电战会议。INRC今后的会议将采用类似的形式。只要有可能,我们计划与其他共同感兴趣的会议重叠。例如,今年计划与国际大麻素研究学会在瑞典举行的会议重叠一天,明年计划与美国药物依赖问题学院重叠三天。对于来自许多国家的与会者来说,INRC是他们在各自领域见面和交流想法的唯一机会。我们认为,许多博士后和博士后实习生的参与已经导致并可能继续导致招募有前途的科学家从事药物滥用研究。
英文摘要
This grant application is to request support for the 41st-45th annual International Narcotics Research Conferences (INRC). The 41st meeting is to be held in Malmo, Sweden from July 11-16, 2010, and will be a satellite meeting to the IUPHAR meeting. The 42nd INRC, which will be a joint meeting with CPDD, will be held in Hollywood, Florida, USA. Plans are underway to finalize venues for the 43rd-45th INRCs. These conferences have been, for many years, the most prestigious international meetings for the dissemination and exchange of information about biomedical research on opiate drugs and the endogenous opioid system. The topics have ranged from molecular mechanisms to behavioral studies and clinical findings. Support is requested primarily for partial travel support to enable young scientists, i.e. graduate students, postdoctoral fellows, and junior faculty, to participate in the Conference. Invited symposium speakers, not normally INRC participants, will receive partial support. Funds requested for administrative and meeting expenses represent ~10% of the total requested funds. The plenary speakers for this year's meeting are: Prof. Tomas Hockfelt (Karolinska, Inst, Sweden), Prof. Tony Yaksh (UCSF, USA) and Prof Jorgen Engel (G"teborg Univ., Sweden). Ten symposia will cover a wide range of topics as described in the application ranging from novel opioid ligands, epigenetics of opioid peptides and receptors, opioids in neuropathic pain, alcohol & gambling addictions and opioid-cannabinoid interactions. A number of relevant contributed papers will be chosen for oral presentation by junior investigators at each symposium. There will be two poster sessions, at which there is always much exchange and discussion. A Data-Blitz session for young scientists is also planned. Future INRC meetings will follow a similar format. Whenever possible, we plan to overlap with other conferences of mutual interest. For example, this year an overlapping day with the International Cannabinoid Research Society meeting in Sweden is planned and next year a 3 day overlap with the College on Problems of Drug Dependence in USA is planned. For participants from many countries, INRC is their only chance to meet and exchange ideas in their field. We feel that participation by many pre- and post- doctoral trainees has resulted, and is likely to continue to result, in recruiting promising scientists to a career of drug abuse research.
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Enhancement of the endogenous opioid system by ketamine
Identifying endogenous peptide ligands for orphan G protein-coupled receptors to explore their roles in CNS disorders
Identifying endogenous peptide ligands for orphan G protein-coupled receptors to explore their roles in CNS disorders
Targeted Deorphanization of G Protein-Coupled Receptors
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